Last update 07 Mar 2026

MORAb-066

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anticancer monoclonal antibody (MORAb-066) - Janssen Biotech/Morphotek, MORAB 066, MORAB-006
Target
tissue factor
Action
inhibitors
Mechanism
tissue factor inhibitors(Tissue factor inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [3]
Active Indication-
Inactive Indication
AdenocarcinomaBreast CancerColorectal Cancer+ [3]
Originator Organization
Janssen Biotech, Inc.Janssen Biotech, Inc.
Active Organization-
Inactive Organization
Morphotek, Inc.Morphotek, Inc.Janssen Global Services LLCJanssen Global Services LLC
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with MORAb-066
NCT01761240
/ CompletedPhase 1
A Phase I Study of the Safety, Tolerability, and Pharmacokinetics of MORAb-066, a Humanized Monoclonal Antibody to Human Tissue Factor, in Patients With Advanced or Metastatic Breast, Pancreatic, Colorectal, or Non-Small Cell Lung Cancer (Adenocarcinoma) Malignancies
100 Clinical Results associated with MORAb-066
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100 Translational Medicine associated with MORAb-066
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100 Patents (Medical) associated with MORAb-066
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100 Deals associated with MORAb-066
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AdenocarcinomaPhase 1
United States
Morphotek, Inc.Morphotek, Inc.
19 Jun 2013
Tissue AdhesionsPhase 1
United States
Morphotek, Inc.Morphotek, Inc.
19 Jun 2013
Breast CancerPhase 1
United States
Morphotek, Inc.Morphotek, Inc.
19 Jun 2013
Colorectal CancerPhase 1
United States
Morphotek, Inc.Morphotek, Inc.
19 Jun 2013
Non-Small Cell Lung CancerPhase 1
United States
Morphotek, Inc.Morphotek, Inc.
19 Jun 2013
Pancreatic CancerPhase 1
United States
Morphotek, Inc.Morphotek, Inc.
19 Jun 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT01761240 (CTgov)
Phase 1
Tissue Adhesions | Adenocarcinoma | Breast Cancer ...
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27
(MORAb-066 0.1 mg/kg)
zwydnrfosg = wlhetmtkow inraauaioj (hstvvjjooq, cebjuripvd - kyjnnxmgtg)
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-
29 Mar 2024
(MORAb-066 0.3 mg/kg)
zwydnrfosg = jtqytrhobk inraauaioj (hstvvjjooq, wwiwljjubj - luxfsxjlcs)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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