Last update 07 Nov 2024

SPR-720

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fobrepodacin, Fobrepodacin(USAN)
Mechanism
Bacterial DNA gyrase inhibitors
Active Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC21H26FN6O6P
InChIKeyCOTQDURISRILOR-CQSZACIVSA-N
CAS Registry1384984-31-9

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Mycobacterium Infections, NontuberculousPhase 2
US
14 Dec 2022
Lung DiseasesPhase 2
US
03 Dec 2020
Mycobacterium Avium-Intracellulare InfectionPhase 2
US
03 Dec 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
16
kytswnaorm(pmjyxhsard) = In evaluating the totality of both the efficacy and safety data, the Company has elected to suspend its current development program for SPR720 and will evaluate other potential paths forward as the remaining data are collected and analyzed. xazxzogche (iiksysmovn )
Not Met
Negative
29 Oct 2024
Phase 1
-
30
hrfunofqxd(qiwfuxvgvj) = When corrected for protein binding, the ratios of ELF to unbound plasma concentrations of SPR719 for AUC0-24 and Cmax were 19.87 and 21.88, and the ratios of AM to unbound plasma concentrations of SPR719 for AUC0-24 and Cmax were 42.50 and 52.53, respectively. omyixkqhur (zwhqghzolv )
Positive
01 Oct 2024
Phase 2
2
Placebo
bthlyzdadz(bfcwkwgdsd) = lggdebhdwa olexcfqmkv (nigdddacot, blgmrnmqnt - qwpxduddcb)
-
28 Feb 2022
Phase 1
96
twkngozcwn(qdfmucltdb) = qbjjhquzcl qhtboxxjkj (qoxshnwjzp )
Positive
18 Oct 2021
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Regulation

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