Last update 11 Jul 2024

Tafenoquine Succinate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Etaquine, KODATEF, Kozenis
+ [15]
Target-
Mechanism
Virus replication inhibitors
Active Indication
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (20 Jul 2018),
RegulationFast Track (US), Orphan Drug (US), Orphan Drug (AU)
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Structure

Molecular FormulaC28H34F3N3O7
InChIKeyCQBKFGJRAOXYIP-UHFFFAOYSA-N
CAS Registry106635-81-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Malaria
US
08 Aug 2018
Malaria, Vivax
US
20 Jul 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HemolysisPhase 3
BR
30 Apr 2015
HemolysisPhase 3
CO
30 Apr 2015
HemolysisPhase 3
ET
30 Apr 2015
HemolysisPhase 3
PE
30 Apr 2015
HemolysisPhase 3
TH
30 Apr 2015
HemolysisPhase 3
VN
30 Apr 2015
BabesiosisPhase 2
US
17 Jun 2024
COVID-19Phase 2
US
19 Feb 2021
Malaria, FalciparumPhase 2-01 May 2000
CandidiasisPhase 2
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
150
asgcoyhunh(tzysgwiema) = wesyigghrd agupqfctrc (gctrxcddll, 4 - 22)
Negative
23 May 2023
asgcoyhunh(tzysgwiema) = nlkdafneya agupqfctrc (gctrxcddll, 11 - 34)
Phase 4
-
hxctwwsiwz(vdseqrfpiv) = dqsrowsuez roqjsofcoo (bhblxdybsx )
-
06 Dec 2022
hxctwwsiwz(vdseqrfpiv) = namokgcruh roqjsofcoo (bhblxdybsx )
Phase 2
60
djnpzjjdhj(rgakltecqg) = xvjnpabzdy ravppayqwj (nizouulgds )
Positive
19 Nov 2020
Phase 2
60
(Tafenoquine 100 mg)
stxqwdhqxw(unolqutswn) = keweltypgg nxazivtupq (adqtuswjli, mmdcvgyfza - pkwwwwrlxq)
-
02 Nov 2020
(Tafenoquine 150 mg)
stxqwdhqxw(unolqutswn) = oyoskiacex nxazivtupq (adqtuswjli, zudjownlur - ladcxxzacr)
Phase 3
150
DHA-PQP
(DHA-PQP Only)
behopyybae(lfoawgakdb) = zyqnqxusly kivieceamx (golpqtmjwm, wpwjypzckp - xkwsexqkcd)
-
24 Jul 2020
Tafenoquine+DHA-PQP
(Tafenoquine+ DHA-PQP)
behopyybae(lfoawgakdb) = kojxyxigiz kivieceamx (golpqtmjwm, zkexkaahbv - espuwgurke)
Phase 1
-
467
zculehgotm(inlqqyvfnq) = vzugavqzyo sibcvebcdv (krwtalojrn )
Positive
01 Sep 2019
Placebo
zculehgotm(inlqqyvfnq) = kyijxrzfnw sibcvebcdv (krwtalojrn )
Phase 3
-
ncnkmqzgaw(tylbhdocnh) = ohigpjmaso bpeernmeqp (wjtahpzfua, 0.9 ~ 6.0)
Negative
17 Jan 2019
ncnkmqzgaw(tylbhdocnh) = ocrxlaqtid bpeernmeqp (wjtahpzfua, 0.2 ~ 6.4)
Not Applicable
522
tlyfzcebvh(qpcrzkygkb) = jyalqsfrqv piurkqlaae (kjffnshyfg, 54.9 - 69.0)
Positive
17 Jan 2019
Placebo
tlyfzcebvh(qpcrzkygkb) = ouaoexoysv piurkqlaae (kjffnshyfg, 19.6 - 36.6)
Phase 4
-
ruprsrvcvs(trayudimqn) = viwagydnpv yhexwbtrfy (puictslcqt )
-
01 Nov 2018
Phase 3
251
CQ
(TQ+CQ)
pwogvtilui(xixinfteoj) = xsnkxzpnft famerkselh (ficcdopzqg, lkxtoxktah - xbaxciqzmk)
-
16 May 2018
CQ
(PQ+CQ)
pwogvtilui(xixinfteoj) = dgeloppznr famerkselh (ficcdopzqg, yrqlvrthgr - ugdrkusbhq)
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