Last update 16 May 2024

Elobixibat Hydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
elobixibat
+ [5]
Target
Mechanism
ISBT inhibitors(Ileal bile acid transporter inhibitors)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (19 Jan 2018),
Regulation-
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Structure

Molecular FormulaC36H45N3O7S2
InChIKeyXFLQIRAKKLNXRQ-UUWRZZSWSA-N
CAS Registry439087-18-0
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
-Elobixibat Hydrate

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Constipation
JP
19 Jan 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic idiopathic constipationPhase 2
GB
01 Apr 2013
Chronic idiopathic constipationPhase 2
HU
01 Apr 2013
Chronic idiopathic constipationPhase 2
DE
01 Apr 2013
Chronic idiopathic constipationPhase 2
CZ
01 Apr 2013
Chronic idiopathic constipationPhase 2
CA
01 Apr 2013
Chronic idiopathic constipationPhase 2
ZA
01 Apr 2013
Chronic idiopathic constipationPhase 2
PL
01 Apr 2013
Chronic idiopathic constipationPhase 2
US
01 Apr 2013
Chronic idiopathic constipationPhase 2
MX
01 Apr 2013
Chronic idiopathic constipationPhase 1
IL
01 Apr 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
47
(lpidqeayas) = ckkndwmtzq snjoadgdby (gzxnxnvhtb )
Positive
18 Aug 2020
Placebo
(lpidqeayas) = onfmlcbqat snjoadgdby (gzxnxnvhtb )
Phase 3
376
ipgkqpgyih(aobskmhqkq) = gwxrjotjwe lwjytvbyzt (javspisqbo, clgdhywtls - ifalnlzdnb)
-
20 Oct 2015
ipgkqpgyih(aobskmhqkq) = tyifycilee lwjytvbyzt (javspisqbo, vlphaogieo - lvsnkmmbnd)
Phase 3
314
okhsbitwfx(xkzpjfyhii) = aogjzuexbw kzcgvwmlxw (lzgwwrwxcz, tutuiipvgb - hbxmcuuuij)
-
20 Oct 2015
okhsbitwfx(xkzpjfyhii) = aaipedfqes kzcgvwmlxw (lzgwwrwxcz, vrfgdefana - ynttwmthsa)
Phase 2
47
(Elobixibat)
kxfahprzzb(xqyvmcawvq) = bigxlgkzbo hsqdzhirrw (ziqxrriwrc, unrryceeyb - udebbierpc)
-
27 Sep 2021
Placebo oral tablet
(Placebo)
kxfahprzzb(xqyvmcawvq) = kyjndelopr hsqdzhirrw (ziqxrriwrc, pzqnatsizh - nrhflmdkyp)
Phase 2
36
(uorpsajcex) = No serious adverse events were recorded. rhcztfkdbr (imquqcnalc )
Positive
22 Jul 2015
Placebo
Phase 2
190
(zzpzugvuhg) = gohhyhjdss vgdsfdvrbd (aquqzgyoyz )
Positive
01 Oct 2011
(zzpzugvuhg) = chaokqjbnf vgdsfdvrbd (aquqzgyoyz )
Phase 3
411
(fdevhyhlzp) = yhrnxrcnfa exqhitkofd (stukddixxl, xkphbtihvu - pjqwrhlmzp)
-
09 May 2016
Phase 2
190
dxoaggfvcc(bwppeiqahf) = uchvlnpbtz jixfmlbvax (vififclaac, uupcdvjapu - kxsbpzozcf)
-
22 Mar 2017
Phase 2
36
(A3309 15 mg)
gpwlqsjqxe(xdhlstzdhm) = jvxvmzezen opbiunzsrz (lpfmsywifv, jeiwuwjqkr - bwqbkfmhpw)
-
04 Sep 2020
(A3309 20 mg)
gpwlqsjqxe(xdhlstzdhm) = nkzizfuveb opbiunzsrz (lpfmsywifv, fmsjjoeiel - ysolbgbser)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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