Last update 18 Jun 2025

18F-GE226

Overview

Basic Info

Drug Type
Affibody, Diagnostic radiopharmaceuticals
Synonyms
luorine18 GE 226, 18FFBAZHER22891, GE 226
+ [1]
Target
HER2
Action
antagonists
Mechanism
HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Locally advanced breast cancer
Inactive Indication-
Originator Organization
Affibody ABAffibody ABGE Healthcare Ltd. (United Kingdom)
Active Organization
Imperial College LondonImperial College London
Inactive Organization
GE Healthcare Ltd. (United Kingdom)
License Organization-
Drug Highest PhaseClinical
First Approval Date-
Regulation-

Related

1
Clinical Trials associated with 18F-GE226
NCT03827317
/ RecruitingNot ApplicableIIT
HERPET: A Mechanistic Non-Invasive Imaging Study of HER2 Expression in Breast Cancer Using [18F]GE-226 Positron Emission Tomography
100 Clinical Results associated with 18F-GE226
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100 Translational Medicine associated with 18F-GE226
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100 Patents (Medical) associated with 18F-GE226
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100 Deals associated with 18F-GE226
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Locally advanced breast cancerClinical
United Kingdom
Imperial College LondonImperial College London
08 Mar 2019
Breast CancerPreclinical
United Kingdom
GE Healthcare Ltd. (United Kingdom)
15 Apr 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03827317 (HERPET, ASCO2022)
ManualManual
Not Applicable
Breast Cancer
HER2 Positive
20
(HER2 positive)
cvgvtvpgyv(wqhkjiicgw): P-Value = <0.001
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Positive
02 Jun 2022
(HER2 negative)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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