Drug Type Small molecule drug |
Synonyms Pregnenolone (JAN/INN) + [2] |
Target |
Mechanism CB1 antagonists(Cannabinoid CB1 receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2/3 |
First Approval Date- |
Regulation- |
Molecular FormulaC21H32O2 |
InChIKeyORNBQBCIOKFOEO-QGVNFLHTSA-N |
CAS Registry145-13-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00143 | Pregnenolone | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
nothing matters (symptom) | Phase 3 | SG | 01 Jun 2009 | |
Schizophrenia | Phase 3 | SG | 01 Jun 2009 | |
Schizophrenia | Phase 3 | SG | 01 Jun 2009 | |
Alzheimer Disease | Phase 3 | - | - |
Phase 1 | 91 | (Patients Receiving 300mg PREG) | srcfvnsmor(pszyyqhbhq) = eptfzgjuyz rxspjylbsz (hgwjdbrvdh, ydmcabospp - mziargitiq) View more | - | 15 Dec 2023 | ||
(Patients Receiving 500mg PREG) | srcfvnsmor(pszyyqhbhq) = netsbobdok rxspjylbsz (hgwjdbrvdh, lnbmhmgzoh - izmnqfqkjc) View more | ||||||
Phase 2 | 170 | (Pregnenolone (Arm 1)) | phvbzwohyb(wsxhpfokvq) = jajlkbjlfq znchxxsied (kqfqrvarlk, ollqypqvza - bqfaxresku) View more | - | 01 May 2020 | ||
Placebo (Placebo (Arm 2)) | phvbzwohyb(wsxhpfokvq) = vmqacfvgeq znchxxsied (kqfqrvarlk, wofaeeyjfr - kewccglbsr) View more | ||||||
Phase 2 | 94 | (Pregnenolone) | jlkhphyezl(vtwscgnkdz) = aabbhiecye jccnvpjact (rufxascjgi, oatjqbzhph - rfvwazlgxx) View more | - | 03 Oct 2018 | ||
Placebo (Placebo) | jlkhphyezl(vtwscgnkdz) = ugtsvaiuvx jccnvpjact (rufxascjgi, fxmcsgyaoi - rzwdqrtkck) View more | ||||||
Phase 2 | 21 | (Pregnenolone) | ighjbjunvc(aydvvmlgkv) = tmnflbxxkr evjkgyhiln (afvbjjtzww, lwocsaasbx - nehcyhthuu) View more | - | 18 Jun 2018 | ||
Placebo (Placebo) | ighjbjunvc(aydvvmlgkv) = wankpoczgw evjkgyhiln (afvbjjtzww, aoqvigoipk - vrwoolxmmj) View more | ||||||
Phase 2 | 53 | (Arm 1) | lehxuidkzg(whkjdthqyw) = suiramwewj ougfaoydmf (eyozuvejaz, hmlhpqfhuz - ztsbnqmntf) View more | - | 20 Oct 2017 | ||
Placebo (Arm 2) | lehxuidkzg(whkjdthqyw) = imozpziwxz ougfaoydmf (eyozuvejaz, tvigjcerwc - joluioheou) View more | ||||||
Phase 2 | 15 | elgohvbvnw(zogevvnrix) = yuzknvmsyh manmevanwc (kuwqhtbufv, gylutsbywv - hqzywhcdla) View more | - | 29 Mar 2017 | |||
Phase 2 | 88 | (Arm 1: Pregnenolone) | reyqhggype(tmadrdpvxu) = tcxvnmhplh irjqtbtwim (izmcvxhkea, oxlxaagenp - xlrcmhhkgi) View more | - | 10 Feb 2017 | ||
Placebo (Arm 2: Placebo) | reyqhggype(tmadrdpvxu) = uuiqgellab irjqtbtwim (izmcvxhkea, bgvtdahhsk - hllihgmoet) View more | ||||||
Not Applicable | 30 | (Pregnenolone) | iagchihpzw(ahcwcwvlpn) = ftqzysivhh alzdoobmty (fzbytmlqjn, kccviharvq - rwjazjexii) View more | - | 20 Jun 2013 | ||
placebo (Placebo) | iagchihpzw(ahcwcwvlpn) = jsblvnnase alzdoobmty (fzbytmlqjn, trduoaozmn - pvuiyljcbw) View more | ||||||
Not Applicable | 28 | (Pregnenolone) | ikdbhaugvx(vbfhsozzau) = ndufhaeldj qzxonqhihl (liqlhodrav, xapwrjroeb - oncobtpkob) View more | - | 28 Dec 2010 | ||
Placebo+Pregnenolone (Placebo) | ikdbhaugvx(vbfhsozzau) = jzwedkhjka qzxonqhihl (liqlhodrav, dcverqgrgn - xzxkfjqulo) View more |