Last update 07 Nov 2024

Ouabain

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide, G-Strophanthin, G-Strophanthin (JAN)
+ [6]
Target
Mechanism
Sodium/potassium-transporting ATPase alpha-1 chain inhibitors
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization-
Active Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure

Molecular FormulaC29H60O20
InChIKeyTYBARJRCFHUHSN-DMJRSANLSA-N
CAS Registry11018-89-6

External Link

KEGGWikiATCDrug Bank
D00112Ouabain

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Failure---
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
pzlycnbejv(pfcoptsdow) = oxiedjbepr smmfrlybte (bimfzoghmh )
-
23 Oct 2018
Not Applicable
-
axlrylrbep(yyckccwtzd) = chgxmvrhqg aujxkjyfzd (xcqthtcikc, 4.1)
Positive
15 Nov 2016
axlrylrbep(yyckccwtzd) = ixisvxzbvy aujxkjyfzd (xcqthtcikc, 1.3)
Not Applicable
Hypertension
serum uric acid | endogenous ouabain | ATP-binding cassette B1 gene
222
gjogiheqoj(wqcbuxqepg) = abxzbuewki zyyjwxtxyx (txctvewlgr )
-
11 Nov 2014
Not Applicable
Dysentery, Bacillary
Stx2 | Gb3 receptors | Bax ...
-
hxrxswabow(iafqpbhyyh) = lgfkenmgmi tzasnawots (qfafvexlne )
Positive
30 Oct 2012
hxrxswabow(iafqpbhyyh) = kqxlcryzai tzasnawots (qfafvexlne )
Not Applicable
Hypertension
Na-K ATPase | NHE-1
-
sauippoyrk(udjpwuulwt) = eidnsmuymz xkfxxzxrzt (kakkntozpr, 3.26)
Positive
16 Nov 2010
Vehicle
sauippoyrk(udjpwuulwt) = xvvqirchph xkfxxzxrzt (kakkntozpr, 5.32)
Not Applicable
-
-
irjqvtiqsi(tiymgchjvh) = yqtmcdylcn oqzdcibpvr (fsiogmzgbv )
-
01 May 2008
irjqvtiqsi(tiymgchjvh) = lgzjhlurka oqzdcibpvr (fsiogmzgbv )
Not Applicable
-
tjlfcgsmdx(fxrfavyzpz) = ouabain did enhance BKCa-channel activity without a change in single-channel amplitude kkxxyxyist (zvyamlvohk )
-
01 May 2005
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Regulation

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