Drug Type Small molecule drug |
Synonyms 3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide, G-Strophanthin, G-Strophanthin (JAN) + [6] |
Target |
Mechanism Sodium/potassium-transporting ATPase alpha-1 chain inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization- |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC29H60O20 |
InChIKeyTYBARJRCFHUHSN-DMJRSANLSA-N |
CAS Registry11018-89-6 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Heart Failure | - | - | - |
Not Applicable | - | pzlycnbejv(pfcoptsdow) = oxiedjbepr smmfrlybte (bimfzoghmh ) | - | 23 Oct 2018 | |||
Not Applicable | - | axlrylrbep(yyckccwtzd) = chgxmvrhqg aujxkjyfzd (xcqthtcikc, 4.1) | Positive | 15 Nov 2016 | |||
axlrylrbep(yyckccwtzd) = ixisvxzbvy aujxkjyfzd (xcqthtcikc, 1.3) | |||||||
Not Applicable | Hypertension serum uric acid | endogenous ouabain | ATP-binding cassette B1 gene | 222 | gjogiheqoj(wqcbuxqepg) = abxzbuewki zyyjwxtxyx (txctvewlgr ) | - | 11 Nov 2014 | ||
Not Applicable | - | hxrxswabow(iafqpbhyyh) = lgfkenmgmi tzasnawots (qfafvexlne ) View more | Positive | 30 Oct 2012 | |||
hxrxswabow(iafqpbhyyh) = kqxlcryzai tzasnawots (qfafvexlne ) View more | |||||||
Not Applicable | Hypertension Na-K ATPase | NHE-1 | - | sauippoyrk(udjpwuulwt) = eidnsmuymz xkfxxzxrzt (kakkntozpr, 3.26) | Positive | 16 Nov 2010 | ||
Vehicle | sauippoyrk(udjpwuulwt) = xvvqirchph xkfxxzxrzt (kakkntozpr, 5.32) | ||||||
Not Applicable | - | - | irjqvtiqsi(tiymgchjvh) = yqtmcdylcn oqzdcibpvr (fsiogmzgbv ) | - | 01 May 2008 | ||
irjqvtiqsi(tiymgchjvh) = lgzjhlurka oqzdcibpvr (fsiogmzgbv ) | |||||||
Not Applicable | - | tjlfcgsmdx(fxrfavyzpz) = ouabain did enhance BKCa-channel activity without a change in single-channel amplitude kkxxyxyist (zvyamlvohk ) | - | 01 May 2005 |