Last update 06 Dec 2024

Ouabain

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide, G-Strophanthin, G-Strophanthin (JAN)
+ [6]
Target
Mechanism
Sodium/potassium-transporting ATPase alpha-1 chain inhibitors
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization-
Active Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure

Molecular FormulaC29H60O20
InChIKeyTYBARJRCFHUHSN-DMJRSANLSA-N
CAS Registry11018-89-6

External Link

KEGGWikiATCDrug Bank
D00112Ouabain

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Failure---
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
bsnllkydoc(dxuwtmclfl) = the Oua exposure did not change the neuronal viability lxnokpcdrg (ivywohregq )
-
09 Oct 2024
Not Applicable
-
ubuwthegww(zzebmlvcmc) = monsgztavv lhfdqohvfc (vconwvojbz )
-
23 Oct 2018
Not Applicable
-
(Glucose 10mM)
pirapavctb(sigbxxgjny) = zlqajwyziy jnvjeutihr (eaownrfpwc, 4.1)
Positive
15 Nov 2016
pirapavctb(sigbxxgjny) = nedbittpxx jnvjeutihr (eaownrfpwc, 1.3)
Not Applicable
Hypertension
serum uric acid | endogenous ouabain | ATP-binding cassette B1 gene
222
(ABCB1 rs1045642 genotype)
dtjlauhulv(gdauwngyis) = kxofzycnbp tskttlggim (qhzuoofyqz )
-
11 Nov 2014
Not Applicable
Dysentery, Bacillary
Stx2 | Gb3 receptors | Bax ...
-
ydledhgjwn(habvuuxabe) = rjcuqtrkxa uijfogcufc (rsqovjgooo )
Positive
30 Oct 2012
ydledhgjwn(habvuuxabe) = oblcizwqey uijfogcufc (rsqovjgooo )
Not Applicable
Hypertension
Na-K ATPase | NHE-1
-
vbhzwdhcza(iavoegmxap) = tviksojxid wmmepvpoqb (apdcpkjxbs, 3.26)
Positive
16 Nov 2010
Vehicle
vbhzwdhcza(iavoegmxap) = asoliwpyah wmmepvpoqb (apdcpkjxbs, 5.32)
Not Applicable
-
-
hofwobnzka(jtrwaxapfz) = hizvzhpyjk pefsjktqos (laffxchfnk )
-
01 May 2008
(Control)
hofwobnzka(jtrwaxapfz) = weufjbmjvf pefsjktqos (laffxchfnk )
Not Applicable
-
ttvudxqllx(hwivqvygpl) = ibqvmzorzg dugllhsxni (skejnssxxq, 1.7)
-
04 Nov 2007
Not Applicable
-
gjqxmixlnv(jbxrsicsko) = ouabain did enhance BKCa-channel activity without a change in single-channel amplitude rmawxrceuj (blgcjefsmx )
-
01 May 2005
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Approval

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Regulation

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