Last update 12 Sep 2025

TCRT ESO A2 (Axis Therapeutics Limited)

Overview

Basic Info

Drug Type
TCR-T Cell therapy
Synonyms
TCRTESOA2, TCRTESOA2Axis Therapeutics
Target-
Action-
Mechanism
T lymphocyte replacements
Therapeutic Areas
NeoplasmsDigestive System DisordersRespiratory Diseases
Active Indication-
Inactive Indication
Advanced Malignant Solid NeoplasmHead and Neck NeoplasmsHepatocellular Carcinoma+ [4]
Originator Organization
AXISAXIS
Active Organization-
Inactive Organization
Xiangxue Life Science Technology (Guangdong) Co., Ltd.Xiangxue Pharmaceutical Co., Ltd.Xiangxue Pharmaceutical Co., Ltd.Athenex, Inc.Athenex, Inc.
+ [1]
License Organization
Axis Therapeutics Ltd.PharmaEssentia Corp.PharmaEssentia Corp.Guangdong Xiangxue Precision Medical Technology Co., Ltd.Guangdong Xiangxue Precision Medical Technology Co., Ltd.
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with TCRT ESO A2 (Axis Therapeutics Limited)
NCT04878484
/ WithdrawnPhase 1
A Phase 1 Open-label Study to Evaluate the Safety, Tolerability, and Activity of TCRT-ESO-A2 Autologous T Cells Expressing TCR Specific for NY-ESO-1 in Subjects With Advanced Solid Tumors
100 Clinical Results associated with TCRT ESO A2 (Axis Therapeutics Limited)
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100 Translational Medicine associated with TCRT ESO A2 (Axis Therapeutics Limited)
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100 Patents (Medical) associated with TCRT ESO A2 (Axis Therapeutics Limited)
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100 Deals associated with TCRT ESO A2 (Axis Therapeutics Limited)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Head and Neck NeoplasmsPhase 1
China
Xiangxue Pharmaceutical Co., Ltd.Xiangxue Pharmaceutical Co., Ltd.
06 Nov 2021
Hepatocellular CarcinomaPhase 1
China
Xiangxue Pharmaceutical Co., Ltd.Xiangxue Pharmaceutical Co., Ltd.
06 Nov 2021
Lung CancerPhase 1
China
Xiangxue Pharmaceutical Co., Ltd.Xiangxue Pharmaceutical Co., Ltd.
06 Nov 2021
SarcomaPhase 1
China
Xiangxue Pharmaceutical Co., Ltd.Xiangxue Pharmaceutical Co., Ltd.
06 Nov 2021
Squamous Cell CarcinomaPhase 1
China
Xiangxue Pharmaceutical Co., Ltd.Xiangxue Pharmaceutical Co., Ltd.
06 Nov 2021
Advanced Malignant Solid NeoplasmPhase 1-
Athenex, Inc.Athenex, Inc.
11 Aug 2021
Solid tumorPreclinical
United States
AXISAXIS
-
Solid tumorPreclinical
United States
Xiangxue Life Science Technology (Guangdong) Co., Ltd.
-
Solid tumorPreclinical
United States
Athenex, Inc.Athenex, Inc.
-
Solid tumorPreclinical
China
Athenex, Inc.Athenex, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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