Last update 16 Aug 2025

LEAF-1703

Overview

Basic Info

Drug Type
Small molecule drug, Liposomal Drug
Synonyms
Liposomal formulation of alpha-D pentaglutamated pemetrexed-D(L.E.A.F. Pharmaceuticals), LEAF 1703, LEAF1703
Target
TYMS
Action
inhibitors
Mechanism
TYMS inhibitors(Thymidylate synthase inhibitors)
Therapeutic Areas
NeoplasmsEndocrinology and Metabolic DiseaseRespiratory Diseases+ [2]
Active Indication
Breast CancerNon-Small Cell Lung CancerOvarian Cancer
Inactive Indication-
Originator Organization
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
Active Organization
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with LEAF-1703
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100 Translational Medicine associated with LEAF-1703
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100 Patents (Medical) associated with LEAF-1703
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100 Deals associated with LEAF-1703
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPhase 2
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
01 Nov 2024
Non-Small Cell Lung CancerPhase 2
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
01 Nov 2024
Ovarian CancerPhase 2
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
01 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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