Last update 25 Apr 2026

PBF-1650

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PBF 1650
Target
A1R x A3R
Action
antagonists
Mechanism
A1R antagonists(Adenosine A1 receptor antagonists), A3R antagonists(Adenosine A3 receptor antagonists)
Therapeutic Areas
Nervous System DiseasesCongenital DisordersDigestive System Disorders+ [2]
Active Indication
Metabolic Dysfunction Associated SteatohepatitisOculocerebrorenal Syndrome
Inactive Indication
PsoriasisPurpura, Thrombocytopenic, Idiopathic
Originator Organization
Palobiofarma SLPalobiofarma SL
Active Organization
Palobiofarma SLPalobiofarma SL
Inactive Organization-
License Organization
Palobiofarma SLPalobiofarma SLXOMA Royalty Corp.XOMA Royalty Corp.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with PBF-1650
NCT03798236
/ CompletedPhase 1
Randomized, Double Blind, Placebo Controlled "First-in-human" Study to Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-1650 (40 mg, 80 mg, 120 and 240 mg) in Healthy Young Male Volunteers.
100 Clinical Results associated with PBF-1650
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100 Translational Medicine associated with PBF-1650
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100 Patents (Medical) associated with PBF-1650
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100 Deals associated with PBF-1650
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PsoriasisPhase 1
Spain
Palobiofarma SLPalobiofarma SL
10 Dec 2018
Metabolic Dysfunction Associated SteatohepatitisPhase 1-
Palobiofarma SLPalobiofarma SL
-
Oculocerebrorenal SyndromePhase 1
Spain
Palobiofarma SLPalobiofarma SL
-
Purpura, Thrombocytopenic, IdiopathicPreclinical
Spain
Palobiofarma SLPalobiofarma SL
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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