Last update 08 May 2025

PBF-1650

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
A1R x A3R
Action
antagonists
Mechanism
A1R antagonists(Adenosine A1 receptor antagonists), A3R antagonists(Adenosine A3 receptor antagonists)
Therapeutic Areas
Digestive System Disorders
Active Indication
Nonalcoholic Steatohepatitis
Inactive Indication
PsoriasisPurpura, Thrombocytopenic, Idiopathic
Originator Organization
Palobiofarma SLPalobiofarma SL
Active Organization
Palobiofarma SLPalobiofarma SL
Inactive Organization-
License Organization
Palobiofarma SLPalobiofarma SLXOMA Royalty Corp.XOMA Royalty Corp.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with PBF-1650
NCT03798236
/ CompletedPhase 1
Randomized, Double Blind, Placebo Controlled "First-in-human" Study to Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-1650 (40 mg, 80 mg, 120 and 240 mg) in Healthy Young Male Volunteers.
100 Clinical Results associated with PBF-1650
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100 Translational Medicine associated with PBF-1650
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100 Patents (Medical) associated with PBF-1650
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100 Deals associated with PBF-1650
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Nonalcoholic SteatohepatitisPhase 1-
Palobiofarma SLPalobiofarma SL
-
Purpura, Thrombocytopenic, IdiopathicPhase 1
Spain
Palobiofarma SLPalobiofarma SL
-
PsoriasisDiscovery
Spain
Palobiofarma SLPalobiofarma SL
10 Dec 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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