Last update 20 Mar 2025

Pyridoxal Phosphate Hydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate, Avastrem
+ [19]
Action
antagonists
Mechanism
Purinergic P2 receptor antagonists
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (17 Mar 1965),
RegulationRare Pediatric Disease (European Union), Orphan Drug (European Union), Fast Track (United States)
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Structure/Sequence

Molecular FormulaC8H10NO6P
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
CAS Registry54-47-7
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Vitamin B 6 Deficiency
Japan
17 Mar 1965
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pyridoxamine 5-Prime-Phosphate Oxidase DeficiencyPhase 3
United States
23 Nov 2023
Coronary Artery DiseasePreclinical
United States
01 Nov 2006
Coronary Artery DiseasePreclinical
Canada
01 Nov 2006
Reperfusion InjuryPreclinical
United States
01 Nov 2006
Reperfusion InjuryPreclinical
Canada
01 Nov 2006
Diabetes Mellitus, Type 2Preclinical
Canada
01 Aug 2004
HypertensionPreclinical
Canada
01 Aug 2004
Metabolic SyndromePreclinical
Canada
01 Aug 2004
Myocardial InfarctionPreclinical
United States
01 Apr 2004
Myocardial InfarctionPreclinical
Canada
01 Apr 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
TNSALP | PLP | ALP ...
2
(Pre-treatment CSF PLP levels)
uzeaclunkr(yxsosjwamr) = ftfizndbfa epvqvjvpgh (ocazshcdgn )
-
08 May 2020
(Pre-treatment CSF PLP and neurotransmitter levels)
bnrcajebnv(cqrtfugapp) = kiyklmprcn rikaylzvwm (nwnukysbvg )
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Approval

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Regulation

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