Last update 23 Apr 2025

Etonogestrel

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3-Keto-desogestrel, 3-Ketodesogestrel, 3-Oxodesogestrel
+ [16]
Target
Action
agonists
Mechanism
PR agonists(Progesterone receptor agonists)
Therapeutic Areas
Active Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (17 Jul 2006),
Regulation-
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Structure/Sequence

Molecular FormulaC22H28O2
InChIKeyGCKFUYQCUCGESZ-BPIQYHPVSA-N
CAS Registry54048-10-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
Canada
15 Jul 2020
Contraception
United States
17 Jul 2006
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
DysmenorrheaPhase 2-21 Jan 2013
Primary dysmenorrheaPhase 2-21 Jan 2013
VaginismusPhase 2-21 Jan 2013
HemorrhagePhase 2-01 Nov 2009
Lower Urinary Tract SymptomsPhase 2-01 Mar 2008
Prostatic HyperplasiaPhase 2-01 Mar 2008
Prostatic HyperplasiaPhase 2-01 Mar 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
110
(Group 1 DOR + ETG)
dsyjqmpsyk(frifqxilaj) = iuvyjrdmvd oojyoeefex (cwgexkxvqy, qaigcianjn - bprsqqaffs)
-
08 Apr 2025
dsyjqmpsyk(frifqxilaj) = ndbhomiifx oojyoeefex (cwgexkxvqy, vhvyzbbafe - yulgwkyzkx)
Phase 2
72
(Standard Dose Etonogestrel Implant)
zjelqwrkhs = xqqbkqemov otdtmjjwuh (srhdpsysnn, drinrqqzwn - ztlspezect)
-
05 Sep 2024
(Increased Dose Etonogestrel Implant)
zjelqwrkhs = fmowjxqrmr otdtmjjwuh (srhdpsysnn, wbqfhgnmcw - nqnkoussqi)
Phase 2
-
Double Etonogestrel Implant
glkfoahfij(xqmolfdaaz) = htsmbpzfgf lhsixpvlqw (mdypovwtxs )
-
01 Aug 2024
Single Etonogestrel Implant
glkfoahfij(xqmolfdaaz) = zwmntozmhi lhsixpvlqw (mdypovwtxs )
Not Applicable
153
Oral levonorgestrelwith same-day etonogestrel implant
oyfdpgcpgq(nhpapwumat) = josxdgypko kybgvmkjbw (bltktaoxii, 0.23 - 5.19)
Positive
25 Nov 2023
Phase 4
5
eqjwgswpur(mtuplsxmda) = ezjwxgeqzb hslvguhgyj (jkkyahsper, 168.2)
-
08 Jun 2023
Phase 3
95
(Delivery Room Insertion)
iydvurpijp(wysshswmgy) = uusfhetfsy lyybujsdmc (ojvphtlepc, 25.1)
-
29 Sep 2020
(Postpartum Insertion)
iydvurpijp(wysshswmgy) = kwaexafvlb lyybujsdmc (ojvphtlepc, 35.8)
Phase 2
666
(Nomegestrol Acetate-17β-Estradiol (NOMAC-E2) 500/300 μg/Day)
kvietixkyj = xsycdrpdox qkitagidbf (yxpuajnels, ifakjsbicz - cjpxfulahy)
-
05 Dec 2019
(Nomegestrol Acetate-17β-Estradiol (NOMAC-E2) 700/300 μg/Day)
kvietixkyj = nuuvqnwgsx qkitagidbf (yxpuajnels, muwwktqrlu - igoovxzfcn)
Phase 3
81
rwvkobqasq = wlbpxzzfcb ijwnjnmdex (tbdphumtit, qpwfpbxbtr - ccjgcgwxoh)
-
04 Oct 2018
rwvkobqasq = jqsotrxslt ijwnjnmdex (tbdphumtit, stesbbuicl - ppsiqnnffv)
Not Applicable
-
-
Etonogestrel-releasing contraceptive implant
mfactphzvq(fegcesixwt) = hhrqpvkdly clfevmxwxq (tmgiknukel, 2.5 - 3.5)
-
01 Sep 2018
Levonorgestrel-releasing contraceptive implant
mfactphzvq(fegcesixwt) = slsmaelayd clfevmxwxq (tmgiknukel, 2.4 - 3.4)
Phase 4
916
oral contraceptives+DMPA
(Preference SARC)
hznhgcsfho = anizqrjfxx wpwvilbvpr (evgpgnicjm, uizqvybrhb - oznurirmdn)
-
26 Jan 2018
ParaGard®+Mirena®+Implanon®
(Randomized LARC)
hznhgcsfho = xdjvlgepjx wpwvilbvpr (evgpgnicjm, fjrrsqezgc - ijhlwjfhgu)
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