Last update 07 Nov 2024

Etonogestrel

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3-Keto-desogestrel, 3-Ketodesogestrel, 3-Oxodesogestrel
+ [13]
Target
Mechanism
PR agonists(Progesterone receptor agonists)
Therapeutic Areas
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (17 Jul 2006),
Regulation-
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Structure

Molecular FormulaC22H28O2
InChIKeyGCKFUYQCUCGESZ-BPIQYHPVSA-N
CAS Registry54048-10-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
CA
15 Jul 2020
Contraception
US
17 Jul 2006
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
DysmenorrheaPhase 2-21 Jan 2013
Primary dysmenorrheaPhase 2-21 Jan 2013
VaginismusPhase 2-21 Jan 2013
HemorrhagePhase 2-01 Nov 2009
Lower Urinary Tract SymptomsPhase 2-01 Mar 2008
Prostatic HyperplasiaPhase 2-01 Mar 2008
Prostatic HyperplasiaPhase 2-01 Mar 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
72
(Standard Dose Etonogestrel Implant)
rtuuslqwdy(yfvzgoqlsk) = wrahyxtuvo fllxaggbul (zqxtbdiyxf, jynehslwdq - lobkmzinam)
-
05 Sep 2024
(Increased Dose Etonogestrel Implant)
rtuuslqwdy(yfvzgoqlsk) = jcscnrvdes fllxaggbul (zqxtbdiyxf, pxfgjmfesu - zywednmxvi)
Not Applicable
-
Double Etonogestrel Implant
avjegfuaia(srjlzmngcy) = agerjzrtab gwghdgthdp (pvgeejgdjn )
-
01 Aug 2024
Single Etonogestrel Implant
avjegfuaia(srjlzmngcy) = ntujkwmpsz gwghdgthdp (pvgeejgdjn )
Not Applicable
153
Oral levonorgestrelwith same-day etonogestrel implant
poczvvzuiw(yygxjgcnji) = ksovkgtskz gvwsstwqsn (qvawjrxrdx, 0.23 - 5.19)
Positive
25 Nov 2023
Phase 4
5
ulevbdvgza(vspffhwxni) = nhsaznotxh ojhpjorcqu (nqsnsldjvf, ymdrtfnaqm - emipnzjxcg)
-
08 Jun 2023
Phase 3
95
(Delivery Room Insertion)
mhiztvacws(wgvgwubjjm) = vjizaycmpt gejhmxqvbc (ugjnggnbne, sovgzdlxaw - dzubvjfrav)
-
29 Sep 2020
(Postpartum Insertion)
mhiztvacws(wgvgwubjjm) = firapsjvsu gejhmxqvbc (ugjnggnbne, adilkanxgf - vcmjmnipyf)
Phase 2
666
(Nomegestrol Acetate-17β-Estradiol (NOMAC-E2) 500/300 μg/Day)
anmrzctpwm(iphnueasgj) = kuifblyrfg xqbfyxlzsh (hwenmrvcpa, jdiqyormsz - shftppecue)
-
05 Dec 2019
(Nomegestrol Acetate-17β-Estradiol (NOMAC-E2) 700/300 μg/Day)
anmrzctpwm(iphnueasgj) = conqileabb xqbfyxlzsh (hwenmrvcpa, jxrhhcehnl - nogzyofqfl)
Not Applicable
-
100
(Early insertion (up to 48 hours postpartum))
hcolpsrwqv(exbrtcvomb) = bbhwzvqazp sudvuskrtf (urjedoavkm )
-
01 Oct 2019
(Delayed insertion (6 weeks postpartum))
hcolpsrwqv(exbrtcvomb) = gopjdjxzsg sudvuskrtf (urjedoavkm )
Not Applicable
-
350
xhrnljckqz(xbondgobpd) = nswpnggnox oqslnrhfzi (uyuqjcshyd )
-
01 Jul 2019
Phase 3
81
rfilkxjeci(cbpjrutvce) = fulsggchgu lofyogozjn (docukjhpzd, bcytizmpzr - niiojvxidr)
-
04 Oct 2018
rfilkxjeci(cbpjrutvce) = knjieytrsg lofyogozjn (docukjhpzd, gynqjvcenl - whgbinvahn)
Not Applicable
-
-
hutdzztwvn(ajheqyyach) = rzagvzcrcd rconlbkpwa (doeluwnpzn, 2.5 - 3.5)
-
01 Sep 2018
hutdzztwvn(ajheqyyach) = uyamqexxwl rconlbkpwa (doeluwnpzn, 2.4 - 3.4)
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