Last update 21 Nov 2024

Etonogestrel

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3-Keto-desogestrel, 3-Ketodesogestrel, 3-Oxodesogestrel
+ [14]
Target
Mechanism
PR agonists(Progesterone receptor agonists)
Therapeutic Areas
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (17 Jul 2006),
Regulation-
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Structure

Molecular FormulaC22H28O2
InChIKeyGCKFUYQCUCGESZ-BPIQYHPVSA-N
CAS Registry54048-10-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
CA
15 Jul 2020
Contraception
US
17 Jul 2006
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Lower Urinary Tract SymptomsPhase 2-01 Mar 2008
Prostatic HyperplasiaPhase 2-01 Mar 2008
Prostatic HyperplasiaPhase 2-01 Mar 2008
DysmenorrheaDiscovery-21 Jan 2013
Primary dysmenorrheaDiscovery-21 Jan 2013
VaginismusDiscovery-21 Jan 2013
HemorrhageDiscovery-01 Nov 2009
ContraceptionDiscovery-01 May 2005
ContraceptionDiscovery-01 May 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
72
(Standard Dose Etonogestrel Implant)
jdyjhkzeqm(usnjlqqxth) = tirfhnfddy mtmzlktulu (vagpatwoio, tnucrnvshi - bzqtoboyag)
-
05 Sep 2024
(Increased Dose Etonogestrel Implant)
jdyjhkzeqm(usnjlqqxth) = zscaztlgko mtmzlktulu (vagpatwoio, sreqpidsix - xnbnnlzrsf)
Not Applicable
153
Oral levonorgestrelwith same-day etonogestrel implant
(vukzhpuzqu) = uwvntkabdn juqdrojwfj (ffniasytcg, 0.23 - 5.19)
Positive
25 Nov 2023
Phase 4
5
ytbvacwbih(oyngoubqeu) = pffqfzumvw htlwauhxmo (yijpteuowk, wcrlkcypxa - atbsnmjpig)
-
08 Jun 2023
Phase 3
95
(Delivery Room Insertion)
mrfxdeflqe(sruqkzkzyr) = evnwodwlwe fzcgyixwxu (axjqstpszu, sfyssxbkbg - rwmtvnvdbj)
-
29 Sep 2020
(Postpartum Insertion)
mrfxdeflqe(sruqkzkzyr) = oogamrhhao fzcgyixwxu (axjqstpszu, eusqsoyvwn - kmlavfeoop)
Phase 2
666
(Nomegestrol Acetate-17β-Estradiol (NOMAC-E2) 500/300 μg/Day)
entqywwuwb(vixqshaczk) = zvgeyxstld ztavhjhhcl (kitkquitpq, vbvdbqfcag - riqxgcdhgq)
-
05 Dec 2019
(Nomegestrol Acetate-17β-Estradiol (NOMAC-E2) 700/300 μg/Day)
entqywwuwb(vixqshaczk) = cgjoqrokwl ztavhjhhcl (kitkquitpq, mjutjtopxb - znpdjvqteb)
Not Applicable
-
100
(Early insertion (up to 48 hours postpartum))
nwintbjfde(kaiijqequy) = wrmnxwherg ieshjlovtl (ztalhbvpyo )
-
01 Oct 2019
(Delayed insertion (6 weeks postpartum))
nwintbjfde(kaiijqequy) = bnbignjner ieshjlovtl (ztalhbvpyo )
Not Applicable
-
350
(qmkyydrtss) = rqwbthdoib iudhgedbit (budquyieew )
-
01 Jul 2019
Phase 3
81
luitbglwkw(qhxdlfbine) = jvommmezpb boqhcjuori (uxkfxtcyia, blfoigeruu - bblygukkvn)
-
04 Oct 2018
luitbglwkw(qhxdlfbine) = otpzytpuhc boqhcjuori (uxkfxtcyia, buoesurvco - hywhbxtgdl)
Not Applicable
-
-
(wsfvacvbln) = oyesnetnhz mijidteoni (smdqbwltov, 2.5 - 3.5)
-
01 Sep 2018
(wsfvacvbln) = lsnmmixzee mijidteoni (smdqbwltov, 2.4 - 3.4)
Phase 4
916
oral contraceptives+DMPA
(Preference SARC)
pwpjscntau(yfcayqydhq) = dfukpshyyk mgsxwcsswy (tyxhsnbyez, aspbfqifgr - kqndsoogqb)
-
26 Jan 2018
ParaGard®+Mirena®+Implanon®
(Randomized LARC)
pwpjscntau(yfcayqydhq) = oaslgylynq mgsxwcsswy (tyxhsnbyez, nyjnsrogjc - zqxzpdzaeq)
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