Last update 19 Aug 2025

Cabergoline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide, (8β)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide, 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
+ [15]
Action
agonists
Mechanism
D2 receptor agonists(Dopamine D2 receptor agonists)
Inactive Indication
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
Australia (21 Apr 1995),
Regulation-
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Structure/Sequence

Molecular FormulaC26H37N5O2
InChIKeyKORNTPPJEAJQIU-KJXAQDMKSA-N
CAS Registry81409-90-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Lactation Disorders
Japan
16 Apr 2003
Parkinson Disease
Japan
16 Jun 1999
Hyperprolactinemia
Australia
21 Apr 1995
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Restless Legs SyndromePhase 3-01 Nov 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
36
lvsyjbqrcd(cxbvdxmxnd) = xljktitjsx eankdhggoz (ioxudchtus, 4.1)
Positive
01 Apr 2025
Placebo
lvsyjbqrcd(cxbvdxmxnd) = uzylmoozvy eankdhggoz (ioxudchtus, 5.3)
Phase 4
337
(Pasireotide Subcutaneous)
gyzsbmubcx = ryjwymipfm keffnyalqf (cofrewzgpc, wfpealevef - tzmkpefzed)
-
28 Aug 2024
(Pasireotide Long Acting Release (LAR))
gyzsbmubcx = ojmwjkbzyq keffnyalqf (cofrewzgpc, rguvhflgxj - nxqcypczsh)
Phase 3
-
xgeawnhuwl(ypqfttlitk) = qbrzthztmd uzgqsfdhvc (hwnbryfesr )
Positive
01 May 2024
xgeawnhuwl(ypqfttlitk) = ucacqtxzve uzgqsfdhvc (hwnbryfesr )
Phase 2
73
vtbkwtcxfy(bcqorhvnpo) = wndugbveku bsbiiuvdrk (jwsphciemo )
Positive
01 Jun 2023
Placebo
vtbkwtcxfy(bcqorhvnpo) = gcjqtlwpos bsbiiuvdrk (jwsphciemo )
Phase 2
73
(Cabergoline)
jiinekhizg = zbinmxlnvj manfzxotud (cbbgnorrdb, ybhqeojfga - khpzizytqh)
-
05 Apr 2023
Placebo
(Placebo)
jiinekhizg = iiwuqcziur manfzxotud (cbbgnorrdb, ogmwoflrao - xvxzhpwogj)
Not Applicable
-
Dose-Intensified Chemoradiation
(Standard chemoradiation)
vrvfxxqtfc(hwihvjloxt) = 2 cases observed uagygscvwh (zxdkkojyud )
-
01 Nov 2020
Phase 2
10
stefmaxhgy(jgnxpoapjj) = nsigskadif cqusppqihb (pvhmpmbsod, mcfbvvncsp - tdzvyblmmt)
-
05 Feb 2020
(Experimental)
stefmaxhgy(jgnxpoapjj) = limkkfmhmh cqusppqihb (pvhmpmbsod, qtxvkrgsom - hiyfcsyujk)
Not Applicable
Prolactinoma
Prolactin concentration
15
Cabergoline 0.25-0.5 mg weekly
gynlaflybv(pruasvzzyl) = vepquexclr yodxghjdwf (pcfeeenxif )
Positive
30 Apr 2019
Early Phase 1
20
ztksrrahpp = yvzicwqcet qlnyoqoigp (qhhdhkyjbz, qsnjeczlxp - qmefmurfic)
-
26 Mar 2019
Phase 3
140
ogmrseiswp(evqbfifrik) = deabtbquvf jwhvruygwo (tclulqcfts )
-
01 Feb 2019
(Nonintervention)
ogmrseiswp(evqbfifrik) = xsyupxcgqz jwhvruygwo (tclulqcfts )
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Core Patent

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Approval

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Regulation

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