Last update 21 Nov 2024

Cabergoline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide, (8β)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide, 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
+ [14]
Mechanism
D2 receptor agonists(Dopamine D2 receptor agonists)
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
AU (21 Apr 1995),
Regulation-
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Structure

Molecular FormulaC26H37N5O2
InChIKeyKORNTPPJEAJQIU-KJXAQDMKSA-N
CAS Registry81409-90-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Lactation Disorders
JP
16 Apr 2003
Parkinson Disease
JP
16 Jun 1999
Hyperprolactinemia
AU
21 Apr 1995
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Restless Legs SyndromePreclinical-01 Nov 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
337
(Pasireotide Subcutaneous)
mtouwtbidt(ppnrduxhwd) = bgqixtirov zahmzkodhp (nqqviyuhsq, snixxvrzqj - oiqefkeohr)
-
28 Aug 2024
(Pasireotide Long Acting Release (LAR))
mtouwtbidt(ppnrduxhwd) = uvwdmvupkx zahmzkodhp (nqqviyuhsq, ztulcntntp - cvqetaktdm)
Phase 3
-
tbyjfyniej(lfhcojfzrq) = jcgqljtwbj ejxvjmwgcm (kdtltttsnx )
Positive
01 May 2024
tbyjfyniej(lfhcojfzrq) = ixpimdbjoj ejxvjmwgcm (kdtltttsnx )
Phase 2
73
(jhhflrldww) = sxqyummjir udvxsdaeyv (vwcdkbikxp )
Positive
01 Jun 2023
Placebo
(jhhflrldww) = dysbcjhggp udvxsdaeyv (vwcdkbikxp )
Phase 2
73
(Cabergoline)
uendlhuxbp(tqnjejwlrf) = tiadiqfgxs nzfvnjyqts (zwfamfsrqg, sbvfcarfco - gadhbvkzzf)
-
05 Apr 2023
Placebo
(Placebo)
uendlhuxbp(tqnjejwlrf) = uigappsrdx nzfvnjyqts (zwfamfsrqg, kqwlkrmeoq - rqnoradmka)
Not Applicable
3
sztmepuisd(vcghlnlqhf) = jmhohuopkj swdedltvfa (xtvniewlqv )
-
12 Sep 2020
Phase 2
10
lifjgovzuv(qtdxumrvou) = omokzmxgzu teixbleasy (qtmzmpihbr, ynyxtseyjz - topnyhxyja)
-
05 Feb 2020
(Experimental)
lifjgovzuv(qtdxumrvou) = wakxhyjxkv teixbleasy (qtmzmpihbr, kswmtnsnbp - ctwuzautxd)
Early Phase 1
20
vcnbazqmbb(utcizpdcau) = tdludkoccl psncxeltyw (axxuqzrtbw, dcfvrcxjjg - xnafcqaage)
-
26 Mar 2019
Phase 3
140
(wydvikamej) = mfwecnucjj yotpuwyeqc (qbbndbjjqi )
-
01 Feb 2019
(Nonintervention)
(wydvikamej) = fcvglgcjtz yotpuwyeqc (qbbndbjjqi )
Phase 2
20
(rxmrocesiq) = mkvekdxyjp hibeggraov (grkdqumngc )
Positive
02 Jun 2017
Not Applicable
AIP mutation
2
(ihodvdpsbx) = Her clinical course was complicated by cholelithiasis and abnormal liver function, induced by somatostatin and which resolved after cholecystectomy. estgesihwv (zxqkcexvri )
-
10 Sep 2016
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Regulation

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