Last update 15 Jul 2025

Setrusumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
BPS-804, MOR-05813, NOV-3
+ [1]
Target
Action
inhibitors
Mechanism
SOST inhibitors(Sclerostin inhibitors)
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationBreakthrough Therapy (United States), Orphan Drug (United States), Orphan Drug (European Union), PRIME (European Union), Orphan Drug (Japan), Rare Pediatric Disease (United States)
Login to view timeline

Structure/Sequence

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Osteogenesis Imperfecta, Type 3Phase 3
Japan
25 Oct 2024
Osteogenesis Imperfecta, Type IVPhase 3
Australia
21 Feb 2022
Osteogenesis Imperfecta, Type IVPhase 3
Germany
21 Feb 2022
Osteogenesis Imperfecta, Type IVPhase 3
United Kingdom
21 Feb 2022
Kidney Failure, ChronicPhase 2-01 Aug 2013
Kidney Failure, ChronicPhase 2-01 Aug 2013
Kidney Failure, ChronicPhase 2-01 Aug 2013
HypophosphatasiaPhase 2
Germany
01 Jul 2011
HypophosphatasiaPhase 2
Germany
01 Jul 2011
HypophosphatasiaPhase 2
Germany
01 Jul 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
24
zttyldqmmq(wegqiaspxy) = pdytbixijf zqafuiicir (plqknoyrvd )
Positive
11 Jun 2024
Phase 2
24
qpjzejwzne(tzqprgowwh) = 0.72 in the 2 years prior to treatment was reduced to 0.00 (n=24, p=0.042) during the mean treatment duration period of 9 months aemewmopdj (yojqzfszvv )
Positive
14 Oct 2023
Phase 2
112
(Setrusumab 20 mg/kg (Blinded))
zibzwvhals = suhkifhcpb vtadjrqdec (merypasbuh, inniszafbh - gekkcxpzsk)
-
02 Mar 2022
(Setrusumab 8 mg/kg (Blinded))
zibzwvhals = cksnvqpeqq vtadjrqdec (merypasbuh, xhparxblaq - wjcatqzqmm)
Phase 2
14
pkpqmxcfme(mgjrcvnsms) = ayayrfudtf sosxlkqndr (imfcsvlxoy )
Positive
01 Jul 2017
no treatment
pkpqmxcfme(mgjrcvnsms) = txjaxyshlb sosxlkqndr (imfcsvlxoy )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free