Drug Type Monoclonal antibody |
Synonyms BPS-804, MOR-05813, NOV-3 + [1] |
Target |
Action inhibitors |
Mechanism SOST inhibitors(Sclerostin inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
RegulationBreakthrough Therapy (United States), Orphan Drug (United States), Orphan Drug (European Union), PRIME (European Union), Orphan Drug (Japan), Rare Pediatric Disease (United States) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Osteogenesis Imperfecta, Type 3 | Phase 3 | Japan | 25 Oct 2024 | |
Osteogenesis Imperfecta, Type IV | Phase 3 | Australia | 21 Feb 2022 | |
Osteogenesis Imperfecta, Type IV | Phase 3 | Germany | 21 Feb 2022 | |
Osteogenesis Imperfecta, Type IV | Phase 3 | United Kingdom | 21 Feb 2022 | |
Kidney Failure, Chronic | Phase 2 | - | 01 Aug 2013 | |
Kidney Failure, Chronic | Phase 2 | - | 01 Aug 2013 | |
Kidney Failure, Chronic | Phase 2 | - | 01 Aug 2013 | |
Hypophosphatasia | Phase 2 | Germany | 01 Jul 2011 | |
Hypophosphatasia | Phase 2 | Germany | 01 Jul 2011 | |
Hypophosphatasia | Phase 2 | Germany | 01 Jul 2011 |
Phase 2/3 | 24 | zttyldqmmq(wegqiaspxy) = pdytbixijf zqafuiicir (plqknoyrvd ) View more | Positive | 11 Jun 2024 | |||
Phase 2 | 24 | qpjzejwzne(tzqprgowwh) = 0.72 in the 2 years prior to treatment was reduced to 0.00 (n=24, p=0.042) during the mean treatment duration period of 9 months aemewmopdj (yojqzfszvv ) View more | Positive | 14 Oct 2023 | |||
Phase 2 | 112 | (Setrusumab 20 mg/kg (Blinded)) | zibzwvhals = suhkifhcpb vtadjrqdec (merypasbuh, inniszafbh - gekkcxpzsk) View more | - | 02 Mar 2022 | ||
(Setrusumab 8 mg/kg (Blinded)) | zibzwvhals = cksnvqpeqq vtadjrqdec (merypasbuh, xhparxblaq - wjcatqzqmm) View more | ||||||
NCT01417091 (Pubmed) Manual | Phase 2 | 14 | pkpqmxcfme(mgjrcvnsms) = ayayrfudtf sosxlkqndr (imfcsvlxoy ) View more | Positive | 01 Jul 2017 | ||
no treatment | pkpqmxcfme(mgjrcvnsms) = txjaxyshlb sosxlkqndr (imfcsvlxoy ) View more |