Last update 18 Oct 2025

RD14-01(Peking University)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
RD14 01, RD14-01
Target
ROR1
Action
antagonists
Mechanism
ROR1 antagonists(Inactive tyrosine-protein kinase transmembrane receptor ROR1 antagonists)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
Advanced Malignant Solid NeoplasmB-cell lymphoma refractoryDiffuse Large B-Cell Lymphoma+ [3]
Originator Organization
Peking UniversityPeking University
Active Organization-
Inactive Organization
Zhejiang UniversityZhejiang UniversityPeking UniversityPeking University920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
License Organization-
Drug Highest PhaseDiscontinuedPhase 1/2
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with RD14-01(Peking University)
NCT05748938
/ Unknown statusPhase 1/2IIT
A Phase1/phase2，Single-arm, Open-label Study of RD14-01 in Patients With Advanced Solid Tumors
NCT05638828
/ Unknown statusEarly Phase 1IIT
A Study of RD14-01 in Patients With Advanced Solid Tumors
NCT05444322
/ Unknown statusEarly Phase 1IIT
A Study of RD14-01 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
100 Clinical Results associated with RD14-01(Peking University)
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100 Translational Medicine associated with RD14-01(Peking University)
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100 Patents (Medical) associated with RD14-01(Peking University)
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100 Deals associated with RD14-01(Peking University)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Locally Advanced Malignant Solid NeoplasmPhase 2
China
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
08 Feb 2023
Advanced Malignant Solid NeoplasmPhase 1-
Peking UniversityPeking University
01 Dec 2022
B-cell lymphoma refractoryPhase 1
China
Zhejiang UniversityZhejiang University
05 Jul 2022
Diffuse Large B-Cell LymphomaPhase 1
China
Zhejiang UniversityZhejiang University
05 Jul 2022
Follicular LymphomaPhase 1
China
Zhejiang UniversityZhejiang University
05 Jul 2022
Mantle-Cell LymphomaPhase 1
China
Zhejiang UniversityZhejiang University
05 Jul 2022
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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