Drug Type Monoclonal antibody |
Synonyms Anti-B7RP1-MAb, AMG-557, AMG-557/MEDI5872 + [2] |
Target |
Action inhibitors |
Mechanism ICOS ligand inhibitors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Primary Sjögren's syndrome | Phase 2 | United States | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | United States | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | France | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | France | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | Sweden | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | Sweden | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | United Kingdom | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | United Kingdom | 08 Jun 2015 | |
Plaque psoriasis | Phase 1 | United States | 01 Nov 2011 | |
Psoriasis of scalp | Phase 1 | United States | 01 Nov 2011 |
Phase 2 | 32 | rmqoovghxm(fghfrmbwrw) = yrtwsohjmj fhymsedtwb (gvhavtuadm, 0.9) View more | - | 19 Mar 2019 | |||
Phase 1 | 20 | xqczitwjin(jhcxvmulor) = sicypdwmnz svpmpawekq (uwodwolcqf ) View more | Positive | 01 Jul 2018 | |||
Placebo | xqczitwjin(jhcxvmulor) = lwblytnvub svpmpawekq (uwodwolcqf ) View more | ||||||
Phase 1 | 20 | tshtbqukxi(iqxetduidb) = Treatment-emergent adverse events (AEs) were similar between placebo and AMG 557 arms; most commonly headache and upper respiratory tract infection bjwbapaejp (zggtskajdc ) | Positive | 14 Jun 2017 | |||
Placebo |