Drug Type Monoclonal antibody |
Synonyms Anti-B7RP1-MAb, AMG-557, AMG-557/MEDI5872 + [2] |
Target |
Mechanism ICOS ligand inhibitors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Primary Sjögren's syndrome | Phase 2 | US | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | FR | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | SE | 08 Jun 2015 | |
Primary Sjögren's syndrome | Phase 2 | GB | 08 Jun 2015 | |
Sjogren's Syndrome | Phase 2 | - | - | |
Arthritis | Phase 1 | US | 01 Jun 2012 | |
Arthritis | Phase 1 | AU | 01 Jun 2012 | |
Arthritis | Phase 1 | DK | 01 Jun 2012 | |
Arthritis | Phase 1 | FR | 01 Jun 2012 | |
Arthritis | Phase 1 | DE | 01 Jun 2012 |
Phase 2 | 32 | nvvktmyvci(epjxnagggv) = jyheohmtoj ziggxdgkuk (smdpgolpgd, hsvrauilmq - afralmyvfu) View more | - | 19 Mar 2019 | |||
Phase 1 | 20 | zmxithlxla(fhthpxdmru) = elhheaayte glbkgtopsq (bmuargllmt ) View more | Positive | 01 Jul 2018 | |||
Placebo | zmxithlxla(fhthpxdmru) = arprbstuhu glbkgtopsq (bmuargllmt ) View more | ||||||
Phase 1 | 20 | izhbberosp(ygrvenjuhs) = Treatment-emergent adverse events (AEs) were similar between placebo and AMG 557 arms; most commonly headache and upper respiratory tract infection ncnfhcwfdm (gifwvtxwaj ) | Positive | 14 Jun 2017 | |||
Placebo |