Last update 16 Aug 2025

LEAF-1401

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LEAF 1401, LEAF-1401
Target
TYMS
Action
inhibitors
Mechanism
TYMS inhibitors(Thymidylate synthase inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [3]
Active Indication
Colorectal CancerBreast CancerHead and Neck Neoplasms+ [3]
Inactive Indication-
Originator Organization
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
Active Organization
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with LEAF-1401
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100 Translational Medicine associated with LEAF-1401
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100 Patents (Medical) associated with LEAF-1401
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100 Deals associated with LEAF-1401
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPreclinical
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
25 May 2020
Colorectal CancerPreclinical
Morocco
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
25 May 2020
Breast CancerPreclinical
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
-
Head and Neck NeoplasmsPreclinical
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
-
Non-Small Cell Lung CancerPreclinical
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
-
Ovarian Epithelial CarcinomaPreclinical
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
-
Pancreatic CancerPreclinical
United States
L.E.A.F. Pharmaceuticals LLCL.E.A.F. Pharmaceuticals LLC
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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