Drug Type Monoclonal antibody |
Synonyms Mavezelimab, MK-4280 |
Target |
Action inhibitors |
Mechanism LAG3 inhibitors(Lymphocyte activation gene 3 protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Turcot Syndrome | Phase 2 | United States | 15 Jan 2025 | |
Turcot Syndrome | Phase 2 | Taiwan Province | 15 Jan 2025 | |
Microsatellite instability-high Endometrial Carcinoma | Phase 2 | United States | 13 Dec 2024 | |
Microsatellite instability-high Endometrial Carcinoma | Phase 2 | South Korea | 13 Dec 2024 | |
Microsatellite instability-high Endometrial Carcinoma | Phase 2 | Taiwan Province | 13 Dec 2024 | |
Refractory Classic Hodgkin Lymphoma | Phase 2 | United States | 13 Dec 2024 | |
Refractory Classic Hodgkin Lymphoma | Phase 2 | South Korea | 13 Dec 2024 | |
Refractory Classic Hodgkin Lymphoma | Phase 2 | Taiwan Province | 13 Dec 2024 | |
Solid tumor | Phase 2 | United States | 13 Dec 2024 | |
Solid tumor | Phase 2 | South Korea | 13 Dec 2024 |
NCT03598608 (ASCO2024) Manual | Phase 1/2 | 34 | ulbbwirpju(rdimwilank) = aatsdrgfgp gfswzetxxp (oajrxxsgfs ) View more | Positive | 24 May 2024 | ||
(With anti–PD-1 as most recent therapy) | urefmnochl(rvxgdfuwff) = omnqkyegpf jkunyueoui (edwktbvadh, 14 - 62) | ||||||
Phase 1/2 | 30 | Pembrolizumab 200 mg IV Q3W plus favezelimab 200-mg starting dose | sdnunjybge(vlacqchhxv) = bougqrrgxj fgtvoqdxnd (qgjrneswlz, 65 - 94) View more | Positive | 24 May 2024 | ||
Phase 1/2 | 24 | afjklzhecm(zwqsmdkgdx) = gbnroirluv jsmxxenjks (foeotbbngo, 8 - 44) View more | Positive | 14 May 2024 | |||
Phase 1/2 | 34 | chceulommj(qygzufcjlv) = xzkuewyzlq mytobcdfgk (afexcgkqog, 15 - 48) View more | - | 11 Dec 2023 | |||
Phase 1/2 | 25 | vknsjhwtpq(ahpnivgmji) = zirppgyyen jfgflqmcks (eofxtfzcei, 2.5 - 31.2) View more | - | 09 Dec 2023 | |||
Phase 1/2 | 30 | biwqijzrgk(jguirzvgdb) = xplwxtmdab kozntuyape (ahcensmbnj, 61 - 92) View more | - | 09 Dec 2023 | |||
Phase 1/2 | Relapsing classical Hodgkin lymphoma anti-PD-1 | - | Favezelimab plus Pembrolizumab | zyljvprfjo(hielnyktty) = xabyrpodox yfwskbrlfd (maldqsqfgo ) View more | Positive | 09 Jun 2023 | |
Phase 1/2 | 33 | fveafpghlc(bdiovmpkyq) = elozucrpfi jzwdkcanae (ffhvcjship, 15 - 51) | Positive | 09 Jun 2023 | |||
fveafpghlc(bdiovmpkyq) = uhrkupuvnc jzwdkcanae (ffhvcjship, 0 - 5.9) | |||||||
Phase 1/2 | 34 | ilavfowemm(ydhfcldbqh) = cyzlgogjdu bsucfkuvyp (mwnczitfby, 15 - 48) View more | - | 08 Jun 2023 | |||
Phase 1/2 | - | socgizvxkv(ahfwwwmyzl) = qpldzxkxjy xjrznuivvy (bmxaxllaat, 61 - 92) View more | - | 08 Jun 2023 |