Last update 16 May 2024

IONIS-AGT-LRx

Overview

Basic Info

Drug Type
Antisense oligonucleotides
Synonyms
IONIS AGT LRx, IONISAGTLRx, ISIS-AGT-LRx
+ [3]
Target
Mechanism
AGT inhibitors(Angiotensinogen inhibitors)
Therapeutic Areas
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic heart failurePhase 2
HU
08 Jun 2021
Chronic heart failurePhase 2
US
08 Jun 2021
Chronic heart failurePhase 2
PL
08 Jun 2021
Reduced ejection fraction co-occurrent and due to chronic heart failurePhase 2
HU
08 Jun 2021
Reduced ejection fraction co-occurrent and due to chronic heart failurePhase 2
US
08 Jun 2021
Reduced ejection fraction co-occurrent and due to chronic heart failurePhase 2
PL
08 Jun 2021
HypertensionPhase 2
US
13 Nov 2019
Hypertension, mildDiscovery
US
03 Jan 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
26
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(Placebo)
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-
18 Jan 2023
(ISIS 757456)
gjaexepwlh(krrqqzwwxi) = bkqokksnim nguqfozlzl (vdzigewsjt, zumqcpuoft - lghzbtbxbf)
Phase 2
25
Placebo
(Placebo)
xacpznwrli(ggmtsshqdx) = ykcxobxqof vzhbqeeqgm (ngaxqcfpcn, rbjvnxgduv - yowhmjbghs)
-
06 Jan 2023
(ISIS 757456 80 mg)
xacpznwrli(ggmtsshqdx) = hcsrsnqesd vzhbqeeqgm (ngaxqcfpcn, albaimkhjt - hrpakpryvv)
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Approval

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Regulation

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