Last update 08 May 2025

Furosemide/Amiloride Chloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Diurisa
Target
ENaCα x NKCC2
Action
inhibitors
Mechanism
ENaCα inhibitors(sodium channel epithelial 1 subunit alpha inhibitors), NKCC2 inhibitors(Sodium-(potassium)-chloride cotransporter 2 inhibitors)
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
Edema, Cardiac
Originator Organization
Eurofarma Laboratórios SAEurofarma Laboratórios SA
Active Organization-
Inactive Organization
Eurofarma Laboratórios SAEurofarma Laboratórios SA
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC6H11Cl2N7O2
InChIKeyWDZJJRLYFQNCQL-UHFFFAOYSA-N
CAS Registry17440-83-4
View All Structures (2)

Related

1
Clinical Trials associated with Furosemide/Amiloride Chloride
NCT01210365
/ TerminatedPhase 3
Safety and Efficacy of the Combination of Furosemide 40 mg + Amiloride Hydrochloride 10 mg in the Reduction of Edema of Cardiac Origin in Patients With Congestive Heart Failure Functional Class II (NYHA)
100 Clinical Results associated with Furosemide/Amiloride Chloride
Login to view more data
100 Translational Medicine associated with Furosemide/Amiloride Chloride
Login to view more data
100 Patents (Medical) associated with Furosemide/Amiloride Chloride
Login to view more data
100 Deals associated with Furosemide/Amiloride Chloride
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Edema, CardiacPhase 3
Brazil
Eurofarma Laboratórios SAEurofarma Laboratórios SA
01 Jan 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free