Synonyms Cardiac Edema, Cardiac Edemas, Cardiac edema + [33] |
Introduction Abnormal fluid retention by the body due to impaired cardiac function or heart failure. It is usually characterized by increase in venous and capillary pressure, and swollen legs when standing. It is different from the generalized edema caused by renal dysfunction (NEPHROTIC SYNDROME). |
Target |
Mechanism CaSR agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. EU [+3] |
First Approval Date11 Nov 2016 |
Target |
Mechanism AVPR2 antagonists |
Active Org. |
Originator Org. |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date19 May 2009 |
Target |
Mechanism NKCC1 inhibitors [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date23 Aug 1993 |
Start Date01 Jun 2024 |
Sponsor / Collaborator |
Start Date10 Jan 2023 |
Sponsor / Collaborator |
Start Date18 May 2019 |
Sponsor / Collaborator |