Development of a multiresidue quantitative screening method based on pulsed amperometric detection at a glassy carbon electrode for sulfonamides monitoring in foodstuffs of animal origin

Article

Author: Croce, Lucia ; Palermo, Carmen ; Centonze, Diego

A new effective quantitative screening method was developed to detect sulfonamides (SAs) in foodstuffs of animal origin. The method was based on pulsed amperometric detection (PAD) at a glassy carbon electrode (GCE) coupled with a reversed-phase high performance liquid chromatographic separation (RP-HPLC). First, SAs electrochemical behaviour at GCE was investigated by cyclic voltammetry (CV) experiments. In the light of the CV results, a new three-step waveform for pulsed amperometric detection of SAs was designed and optimized by performing flow injection analysis (FIA) of SAs standard solutions. The optimized PAD waveform ensured an excellent response stability and sensitivity with respect to the direct current detection at constant potential. PAD was then applied to detect SAs after RP-HPLC in gradient mode by using a typical organic mobile phase containing acetate buffer, acetonitrile and methanol. The developed method showed, for all the SAs investigated, very low limits of detection and quantification, in the range 2.1-2.7 μg L^-1 and 6.9-9.0 μg L^-1, respectively, and a wide linear range (up to 0.5 mg L^-1). Method selectivity was tested by comparing the chromatograms of SAs mix standard solutions, blank purified milk samples (without SAs) and spiked purified milk samples. Excellent values of precision under repeatability (1.0-5.0 %, n = 6) and within-laboratory reproducibility (11.2-18.6 %, n = 18) conditions, and recoveries (94-105 %) were obtained.

01 Aug 2025·Journal of Environmental Sciences

FeCN/MXene as novel heterogeneous electro-Fenton catalysts for the degradation of sulfathiazole: Performance and mechanism investigation

Article

Author: Liu, Huilai ; Li, Zhihao ; Chen, Xing ; Kong, Defeng

The present study aims to fabricate heterogeneous electro-Fenton (HEF) cathode catalysts for the in-situ generation of H₂O₂ and the degradation of organic pollutants in water. To achieve this, preparation of Fe and N co-doped MXene composites (FeCN/MXene-x, where x represents the loading content of FeCN) and construction of the HEF system for the degradation of sulfathiazole (STZ) were carried out. The characterization results showed that Fe, C and N mainly existed in the form of Fe₃C and Fe₃N in the FeCN/MXene catalysts, which were favorable for promoting the ORR reaction in the HEF system. Among them, FeCN/MXene-2 exhibited the highest redox electron transfer rate and H₂O₂ selectivity (86%). The catalytic oxidation mechanism of the FeCN/MXene-2/HEF system was investigated by free radical quenching, electron paramagnetic resonance and frontier orbital theory studies. These studies demonstrated that the main active substances for the degradation of STZ were ·OH and ¹O₂. In addition, the excellent stability and practical performance of the prepared cathodic catalysts were demonstrated by cycling experiments and real water sample tests.

01 Jul 2025·Reactive and Functional Polymers

Containing P/N/B/S multi-element flame retardant epoxy resin: Low smoke, low dielectric strength, UV shielding

Author: Cai, Haopeng ; Peng, Yufei ; Sun, Lanlan ; Wang, Wenbo ; Huang, Wanyu

With the development of rail transit in the direction of high-speed and safety, the multifunctional epoxy resin (EP) featuring flame resistance, low smoke emissions, low dielec. constant and superior UV shielding has excellent development prospects.This study introduced a multifunctional new reactive flame retardant FSD, which, by incorporating P/N/S/B, significantly modified epoxy resin and achieved multi-functional upgrading of the resin.The results showed that the limiting oxygen index (LOI) of the modified epoxy resin EP/FSD7.5 was enhanced to 33.2%, and there was a notable enhancement in the material's fire safety, attributed to a 45.03% reduction in the peak heat release rate (PHRR) and a 44% decrease in total smoke production (TSP).In addition, the introduction of FSD gave EP excellent UV shielding properties and optimized its dielec. properties without sacrificing mech. properties.In particular, in the smoke d. test, the specific optical d. of the fourth minute (DS (4)) and Cumulative smoke concentration in the first four minutes (VOF₄) values for the EP/FSD7.5 composite successfully attained the HL1 classification under the EN45545-2 regulations.The research outcomes offer an innovative approach to advancing rail transit materials, with significant implications and practical application value.

100 Deals associated with Sulfathiazole

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KEGG	Wiki	ATC	Drug Bank
D01047	Sulfathiazole	J01EB07 D06BA02	DB06147

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Indication	Country/Location	Organization	Date
Bacterial Vaginosis	-	-	-
Skin Diseases, Infectious	-	-	-

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