Delving into the Latest Updates on Fibrin glue(Foundation For Biomedical Research And Innovation) with Synapse

Overview

Basic Info

Drug Type

Non-recombinant coagulation factor

Synonyms

Target

Fibrinogen

Action

stimulants

Mechanism

Fibrinogen stimulants

Therapeutic Areas

Otorhinolaryngologic DiseasesOther Diseases

Active Indication

Tympanic Membrane Perforation

Inactive Indication-

Originator Organization

Foundation For Biomedical Research And Innovation

Active Organization

Foundation For Biomedical Research And Innovation

Inactive Organization-

Drug Highest PhasePhase 3

First Approval Date-

Regulation-

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BACKGROUND/AIMTracheal anastomosis is commonly indicated for patients with tracheal tumor, stenosis and tracheoesophageal fistula. This study was designed to evaluate the healing activity of topical application of platelet-rich plasma (PRP) jelly for tracheal reconstruction in a rabbit model.MATERIALS AND METHODSThirty-six healthy New Zealand White rabbits were assigned to three groups of 12 animals each. The control group underwent tracheal resection and anastomosis. The fibrin-glue group and PRP-jelly group underwent tracheal resection and anastomosis plus fibrin glue or PRP jelly application over the anastomosis and surgical field, respectively.RESULTSThe PRP jelly treatment enhanced the healing capacity by positive effects on healing rate, tissue fill, and volume fraction of fibroblasts during the 28 days following surgery.CONCLUSIONApplication of PRP jelly to tracheal anastomotic wounds can accelerate or improve the quality of repair.

100 Deals associated with Fibrin glue(Foundation For Biomedical Research And Innovation)

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Tympanic Membrane Perforation	Phase 3	-	Foundation For Biomedical Research And Innovation	-

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Clinical Result

Indication

Phase

Evaluation

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


P291 (EBMT2018)	Not Applicable	Hemorrhagic cystitis	63	Fibrin-glue	(svongvnkpe) = roacmwwbyb hczjirduvo (juyjpojbzj ) View more	-	19 Nov 2018
AAO2013	Not Applicable	-	23	Fibrin glue-assisted intrascleral fixation of PC-IOL	(vswkqtqqer) = zoeozoytei isryfmkfij (sfpusvrsjg ) View more	Positive	17 Nov 2013
ARVO2002	Not Applicable	Blister	20	Cultured skin + Fibrin glue	(tqwydflaqd) = zbzjllerkm mqfhluaqbc (fwukvrvxcx )	Positive	01 Dec 2002
ARVO2002	Not Applicable	Blister	20	Free Electron Laser-treated Fibrin Glue (Cultured skin + Fibrin glue + FEL @ 7.7µm)	(tqwydflaqd) = wrpyscsaqj mqfhluaqbc (fwukvrvxcx )	Positive	01 Dec 2002

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

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