Last update 19 Jun 2024
CBP-1018
Last update 19 Jun 2024
Overview
Basic Info
Drug Type Small molecule-drug conjugates |
Synonyms CBP 1018, CBP1018 |
Target |
Mechanism FOLR1 antagonists(Folate receptor alpha antagonists), TRPV6 antagonists(Transient receptor potential cation channel subfamily V member antagonists), Immunomodulators |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
Structure
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Related
2
Clinical Trials associated with CBP-1018评价注射用CBP-1018在晚期恶性实体瘤患者中安全性和耐受性、药代动力学及初步疗效的非随机、开放、首次用于人体的Ⅰ期临床研究
[Translation] A non-randomized, open-label, first-in-human Phase I clinical study to evaluate the safety and tolerability, pharmacokinetics, and preliminary efficacy of CBP-1018 for injection in patients with advanced malignant solid tumors
An Open-Label, Non-randomized, Multi-center Phase I Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Bi-Ligand-Drug Conjugate CBP-1018 in Patients With Advanced Solid Tumors
100 Clinical Results associated with CBP-1018
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100 Translational Medicine associated with CBP-1018
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100 Patents (Medical) associated with CBP-1018
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100 Deals associated with CBP-1018
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 1 | CN | 04 Nov 2021 | |
| Lung Cancer | Phase 1 | CN | 05 Nov 2020 | |
| Prostatic Cancer | Phase 1 | CN | 05 Nov 2020 | |
| Bone metastases | Phase 1 | CN | - | |
| Metastatic castration-resistant prostate cancer | IND Approval | US | 12 Jun 2024 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
NCT04928612 (ESMO2023) Manual  | Phase 1 | 20 | ogpujxmppo(uudsiumiov) = uvlxkzelkn pdyxndygwf (alwgqfhatn ) View more | Positive | 22 Oct 2023 | ||
NCT04928612 (ASCO2023) Manual | Phase 1 | 14 | ueritcjfyt(zjhalckbmz) = qlkfrofpuj xlkljrtcbr (belpxzmvoz ) View more | Positive | 26 May 2023 | ||
(mCRPC) | ckwlpvtfmo(csrzisgegs) = wwudhzmbaz dbkqwrinqn (ohsiovmncm ) View more |
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Translational Medicine
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Core Patent
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Clinical Trial
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Approval
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Regulation
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