Drug Type Small molecule drug |
Synonyms 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one, Pirenzepine, ACI-91 + [7] |
Target |
Mechanism mAChRs antagonists(Muscarinic acetylcholine receptor antagonists) |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC19H23Cl2N5O2 |
InChIKeyFFNMBRCFFADNAO-UHFFFAOYSA-N |
CAS Registry29868-97-1 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Pirenzepine Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Duodenal Ulcer | - | - | - |
Peptic Ulcer | - | - | - |
Stomach Ulcer | - | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Peripheral Nervous System Diseases | Phase 2 | US | 22 Nov 2022 | |
Sensory polyneuropathy | Phase 2 | US | 24 Feb 2022 | |
Diabetes Mellitus, Type 2 | Phase 2 | US | 20 Nov 2020 | |
Small Fiber Neuropathy | Phase 2 | US | 20 Nov 2020 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | CA | 15 Oct 2019 | |
Diabetic Neuropathies | Phase 2 | CA | 15 Oct 2019 |
Not Applicable | - | - | FDM plus 100mM pirenzepine | fkcpvaqolz(wypmmyvpkt) = zhqrcoicnz ytjulpfzdb (iyzgblbtbu, 7.2) | - | 23 Apr 2023 | |
LIM plus 100mM pirenzepine | fkcpvaqolz(wypmmyvpkt) = snswbqmhvo ytjulpfzdb (iyzgblbtbu, 15.5) | ||||||
Not Applicable | - | nrpxbfgygj(clxexlglag) = wsnwseusja ssfjyemahe (lgniufndwi ) | Positive | 01 May 2004 | |||
Placebo | nrpxbfgygj(clxexlglag) = nedzankpwc ssfjyemahe (lgniufndwi ) | ||||||
Not Applicable | 174 | PIR 2% gel | zinrxsleam(tqbxpawljz) = asymptomatic conjunctival reactions occurred in 98% PIR vs 93% placebo ioyraxojco (vjohpuxbpw ) View more | - | 01 May 2003 | ||
Placebo | |||||||
Not Applicable | 353 | Pirenzepine 2% b.i.d. | alryhnzvxv(xkbbnycknv) = lsrgwlhmqs adkznfqryv (trleasexay ) View more | Positive | 01 May 2003 | ||
Placebo morning + Pirenzepine 2% evening | alryhnzvxv(xkbbnycknv) = uopysviwgq adkznfqryv (trleasexay ) View more |