Last update 21 Nov 2024

LMY-920

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
Target
BAFF-R x BCMA x TACI
Mechanism
BAFF-R inhibitors(B-cell activating factor receptor inhibitors), BCMA inhibitors(B-cell maturation protein inhibitors), TACI modulators(Tumor necrosis factor receptor superfamily member 13B modulators)
Therapeutic Areas
NeoplasmsImmune System DiseasesCardiovascular Diseases+ [3]
Active Indication
Systemic Lupus ErythematosusPlasma cell myeloma refractoryRelapse multiple myeloma+ [3]
Inactive Indication-
Originator Organization
Luminary Therapeutics, Inc.Luminary Therapeutics, Inc.Startup
Active Organization
Luminary Therapeutics, Inc.Luminary Therapeutics, Inc.StartupThe Case Comprehensive Cancer CenterThe Case Comprehensive Cancer CenterCase Western Reserve UniversityCase Western Reserve University
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with LMY-920
NCT06340750 / Not yet recruitingPhase 1
A Phase I Study of BAFF CAR-T Cells (LMY-920) for Treatment of Systemic Lupus Erythematosus
NCT05546723 / RecruitingPhase 1
LUMT1A22, Phase 1 Study of BAFF CAR T Cells (LMY-920) for Treatment of Relapsed or Refractory Myeloma (LMY-920-002)
NCT05312801 / RecruitingPhase 1
LMY-920 for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma
100 Clinical Results associated with LMY-920
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100 Translational Medicine associated with LMY-920
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100 Patents (Medical) associated with LMY-920
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100 Deals associated with LMY-920
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Systemic Lupus ErythematosusPhase 1
US
Luminary Therapeutics, Inc.Luminary Therapeutics, Inc.Startup
15 Jan 2025
Plasma cell myeloma refractoryPhase 1
US
Luminary Therapeutics, Inc.Luminary Therapeutics, Inc.Startup
13 Mar 2024
Plasma cell myeloma refractoryPhase 1
US
Case Western Reserve UniversityCase Western Reserve University
13 Mar 2024
Relapse multiple myelomaPhase 1
US
Luminary Therapeutics, Inc.Luminary Therapeutics, Inc.Startup
13 Mar 2024
Relapse multiple myelomaPhase 1
US
Case Western Reserve UniversityCase Western Reserve University
13 Mar 2024
B-Cell LymphomaPhase 1
US
The Case Comprehensive Cancer CenterThe Case Comprehensive Cancer Center
21 Nov 2023
Non-Hodgkin's lymphoma refractoryPhase 1
US
The Case Comprehensive Cancer CenterThe Case Comprehensive Cancer Center
21 Nov 2023
Non-Hodgkin's lymphoma refractoryPhase 1
US
Luminary Therapeutics, Inc.Luminary Therapeutics, Inc.Startup
21 Nov 2023
Recurrent Non-Hodgkin LymphomaPhase 1
US
The Case Comprehensive Cancer CenterThe Case Comprehensive Cancer Center
21 Nov 2023
Recurrent Non-Hodgkin LymphomaPhase 1
US
Luminary Therapeutics, Inc.Luminary Therapeutics, Inc.Startup
21 Nov 2023
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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