Last update 29 Nov 2024

AAV-CMV.sflt

Overview

Basic Info

Drug Type
AAV based gene therapy
Synonyms
rAAV.sFlt-1, AVA-101(Adverum)
Target
VEGFR1
Mechanism
VEGFR1 modulators(Vascular endothelial growth factor receptor 1 modulators)
Therapeutic Areas
Eye Diseases
Active Indication
Retinal Neovascularization
Inactive Indication
Wet age-related macular degeneration
Originator Organization
Adverum Biotechnologies, Inc.Adverum Biotechnologies, Inc.
Active Organization
Lions Eye InstituteLions Eye Institute
Inactive Organization
Adverum Biotechnologies, Inc.Adverum Biotechnologies, Inc.
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with AAV-CMV.sflt
NCT01494805 / CompletedPhase 1/2
A Phase I/II Controlled Dose-escalating Trial to Establish the Baseline Safety and Efficacy of a Single Subretinal Injection of rAAV.sFlt-1 Into Eyes of Patients With Exudative Age-related Macular Degeneration (AMD)
100 Clinical Results associated with AAV-CMV.sflt
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100 Translational Medicine associated with AAV-CMV.sflt
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100 Patents (Medical) associated with AAV-CMV.sflt
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100 Deals associated with AAV-CMV.sflt
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Retinal NeovascularizationPhase 2
AU
Adverum Biotechnologies, Inc.Adverum Biotechnologies, Inc.
01 Dec 2011
Wet age-related macular degenerationPhase 2
AU
Adverum Biotechnologies, Inc.Adverum Biotechnologies, Inc.
01 Dec 2011
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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