Last update 24 May 2024

Dimethyltryptamine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-(3-indolyl)ethyldimethylamine, 3-(2-dimethylaminoethyl)indole, 3-[2-(dimethylamino) ethyl] indole
+ [8]
Mechanism
5-HT receptor modulators(Serotonin (5-HT) receptor modulators), Neurons modulators
Inactive Indication-
Originator Organization-
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)

Structure

Molecular FormulaC12H16N2
InChIKeyDMULVCHRPCFFGV-UHFFFAOYSA-N
CAS Registry61-50-7

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Depressive Disorder, Treatment-ResistantPhase 2
BR
BioMindStartup
09 Mar 2022
Depressive Disorder, MajorPhase 2
GB
04 Feb 2021
Depressive DisorderPhase 1
US
01 Oct 2022
Smoking CessationPhase 1
NL
22 Feb 2022
Brain Injuries, TraumaticPhase 1--
StrokePhase 1--
AlcoholismPreclinical
IL
01 Mar 2022
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
17
(SSRI Cohort)
samltazjeo(lctkfhorrq) = egoznrntif bkgezlcaqv (dgijtclpjx )
Positive
26 Sep 2023
(Non-SSRI Cohort)
samltazjeo(lctkfhorrq) = rmrtqxxdzr bkgezlcaqv (dgijtclpjx )
Phase 1
-
-
djteqzjgia(oqiqdopbjb) = SPL026 was well tolerated, with an acceptable safety profile, with no serious adverse events yehcbybsqy (oikofvfvgt )
-
01 Jan 2023
Phase 2
30
krdluljzod(hrcapaayrk) = No volunteer presented serious adverse events to the 11 different doses tested. ovxvdurcwq (jxtvzjbsef )
Positive
04 Nov 2022
Not Applicable
256
Patients treated with immunotherapy until gestation
yjkrfnjoau(ceccoomhjy) = kqkwjrfcxi euysekxpjg (xixfuusugc )
-
10 Sep 2019
Patients who never had a therapy
yjkrfnjoau(ceccoomhjy) = kfpzecuwbd euysekxpjg (xixfuusugc )
Not Applicable
520
kwfsztstce(agtaluppoi) = tnnmhjrnlb rhjqshfcqi (dxhsqirgza )
-
09 Oct 2018
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Regulation

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