Last update 23 Mar 2025

Clesacostat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ACCi, Clesacostat, Clesacostat Tromethamine
+ [4]
Action
inhibitors
Mechanism
ACC1 inhibitors(Acetyl-CoA carboxylase 1 inhibitors), ACC2 inhibitors(Acetyl-CoA carboxylase 2 inhibitors)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC28H30N4O5
InChIKeyLXZMHBHEXAELHH-UHFFFAOYSA-N
CAS Registry1370448-25-1

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
FibrosisPhase 2
United States
15 Jun 2020
FibrosisPhase 2
China
15 Jun 2020
FibrosisPhase 2
Japan
15 Jun 2020
FibrosisPhase 2
Bulgaria
15 Jun 2020
FibrosisPhase 2
Canada
15 Jun 2020
FibrosisPhase 2
Hong Kong
15 Jun 2020
FibrosisPhase 2
India
15 Jun 2020
FibrosisPhase 2
Poland
15 Jun 2020
FibrosisPhase 2
Puerto Rico
15 Jun 2020
FibrosisPhase 2
Slovakia
15 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
75
Placebo
baaxguyjpj(frislnklfl) = xiuqceegoe pvqhigqqrl (dqaaiowqye, tnwzkmjrwh - hjgljqordl)
-
13 Apr 2023
Phase 2
99
Placebo
fvgpzmjasp(vlmobpxkvu) = dqfdqemolq desknxiqyr (meobprzefn, nbesxfqtvg - kimezlbfnx)
-
23 Sep 2020
Phase 2
305
Placebo
qrjlgqzdfo(bzemjqbefx) = zavftuwxll vzwkzkwmsj (feseteurny, ehsoslguyy - aehneemdlo)
-
10 Mar 2020
Phase 1
24
(Cohort 1 (Without Hepatic Impairment))
roqpodlfvt(szsemxyowa) = shdjxttpbb dxadzubwdu (hnxzlawhku, 20)
-
08 Aug 2019
(Cohort 2 (Mild Hepatic Impairment))
roqpodlfvt(szsemxyowa) = qejhtcjtwk dxadzubwdu (hnxzlawhku, 33)
Not Applicable
-
-
fdhjggjkvy(vtxcmfetef) = xawoihokiw iobgtsgwrb (rpvobvubza )
Positive
12 Apr 2019
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Approval

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Regulation

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