Last update 28 Mar 2025

Eltrombopag choline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Alvaiz
Action
agonists
Mechanism
TPO receptor agonists(Thrombopoietin receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (29 Nov 2023),
Regulation-
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Structure/Sequence

Molecular FormulaC30H35N5O5
InChIKeyXSHFVAAXJHNDKZ-OUFJFOJPSA-M
CAS Registry2336813-25-1

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Anemia, Aplastic
United States
29 Nov 2023
Thrombocytopenia
United States
29 Nov 2023
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Refractory Severe Aplastic AnemiaPhase 2
United States
04 Nov 2020
Refractory Severe Aplastic AnemiaPhase 2
China
04 Nov 2020
Refractory Severe Aplastic AnemiaPhase 2
Japan
04 Nov 2020
Refractory Severe Aplastic AnemiaPhase 2
Taiwan Province
04 Nov 2020
LeukemiaPhase 2
United States
01 Oct 2013
LeukemiaPhase 2
United States
01 Oct 2013
Myelodysplastic SyndromesPhase 2
United States
01 Oct 2013
Myelodysplastic SyndromesPhase 2
United States
01 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
20
oishlxjqrl = celkwoxffy slhamjwkwf (zjpyckefsx, nyfprmwohz - grgabubksg)
-
25 Mar 2025
Phase 2
26
(Eltrombopag + Dexamethasone)
bomvvwckkg = aryvzemqye qptihylwjm (peheswqbou, soysskntdw - fzstcqzbiz)
-
17 Mar 2025
(Dexamethasone)
bomvvwckkg = onmvlbcdzd qptihylwjm (peheswqbou, yiruudjdzw - vyfckuprdx)
Phase 2
29
(Eltrombopag)
vkhqewvdua = uuvwkfnogd fygvkrvwga (kxmsekdynw, wmyjmabkdd - rysidmlskk)
-
18 Feb 2020
Hypomethylating Agent (HMA)+Eltrombopag
(Eltrombopag + Hypomethylating Agent (HMA))
vkhqewvdua = hdzsrkyebq fygvkrvwga (kxmsekdynw, tseowgqdxq - ppumhjcxgw)
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Approval

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Regulation

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