HRS-5965

Main research objectives: 1. Quantitatively analyze the total radioactivity in excreta after a single oral administration of [14C] HRS-5965 to healthy subjects, and obtain the recovery rate data and main excretion pathways of human radioactivity; 2. Quantitatively analyze the total radioactivity in whole blood and plasma after a single oral administration of [14C] HRS-5965 to healthy subjects, obtain the pharmacokinetic parameters of total plasma radioactivity, and investigate the distribution of total radioactivity in whole blood and plasma; 3. Quantitatively analyze the radioactive metabolite spectrum of plasma, urine and feces of healthy subjects after a single oral administration of [14C] HRS-5965, identify the main metabolites, and determine the metabolic pathways and elimination pathways of HRS-5965 in the human body.