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Last update 29 Aug 2026
SYHX-1901
Last update 29 Aug 2026
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms SYHX-1901, SYHX1901 |
Target |
Action inhibitors |
Mechanism JAK inhibitors(Janus kinase inhibitors), Syk inhibitors(Spleen tyrosine kinase inhibitors), TYK2 inhibitors(Tyrosine-protein kinase 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Related
14
Clinical Trials associated with SYHX-1901CTR20262580
评价SYHX1901片在轻度、中度肝功能损害和肝功能正常对照参与者中的药代动力学和安全性的开放、平行、多中心临床研究
[Translation] An open-label, parallel, multicenter clinical study evaluating the pharmacokinetics and safety of SYHX1901 tablets in participants with mild to moderate hepatic impairment and controls with normal hepatic function.
ChiCTR2600129491
An Open-label, Parallel-group, Multicenter Clinical Study to Evaluate the Pharmacokinetics and Safety of SYHX1901 Tablets in Participants with Mild, Moderate Hepatic Impairment and Matched Controls with Normal Hepatic Function
CTR20255222
在健康受试者中评估SYHX1901与瑞舒伐他汀、雷贝拉唑、伊曲康唑和利福平的药物相互作用研究
[Translation] A study evaluating the drug interactions of SYHX1901 with rosuvastatin, rabeprazole, itraconazole, and rifampin in healthy subjects.
100 Clinical Results associated with SYHX-1901
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100 Translational Medicine associated with SYHX-1901
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100 Patents (Medical) associated with SYHX-1901
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1
Literatures (Medical) associated with SYHX-190101 Apr 2026JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
SYHX1901, an oral dual Janus kinase and spleen tyrosine kinase inhibitor, for moderate-to-severe plaque psoriasis: A randomized phase 2 trial
Article
Author: Cao, Lei ; Li, Shanshan ; Qin, Xiaomin ; Yu, Guoning ; Cheng, Fang ; Ding, Yangfeng ; Zhang, Shifa ; Zhu, Lili ; Shi, Chunrui ; Kang, Xiaojing ; Zhu, Quangang ; Xu, Jinhua ; Mou, Kuanhou ; Liang, Xiong'an ; Man, Xiaoyong ; Pei, Zejun ; Han, Ling ; Zhang, Furen ; Wu, Shunquan
100 Deals associated with SYHX-1901
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Nonsegmental vitiligo | Phase 3 | China | 06 Feb 2026 | |
| Plaque psoriasis | Phase 3 | China | 04 Jun 2025 | |
| Chronic large plaque psoriasis | Phase 3 | - | 01 Jun 2025 | |
| Alopecia Areata | Phase 3 | China | - | |
| Psoriasis | Phase 3 | China | - | |
| Vitiligo | Phase 3 | China | - | |
| COVID-19 | Phase 1 | China | 23 Nov 2022 | |
| Rheumatoid Arthritis | Phase 1 | China | 15 Jul 2022 | |
| Systemic Lupus Erythematosus | Phase 1 | China | 15 Jul 2022 | |
| Hematologic Neoplasms | IND Approval | China | 13 Jan 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
J Am Acad Dermatol Manual  | Phase 2 | 93 | hhbqwlivmu(bwssmjurfg) = tfltldyobf yihssjeqav (xsjlvduenf ) View more | Positive | 17 Dec 2025 | ||
hhbqwlivmu(bwssmjurfg) = jdpqdogrxw yihssjeqav (xsjlvduenf ) View more |
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