Last update 12 Dec 2024

SHR-A1912

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
SHR A1912, SHR-A1912, SHRA1912
Target
CD79B
Mechanism
CD79B inhibitors(B-cell antigen receptor complex-associated protein beta chain inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
LymphomaB-Cell Lymphoma
Inactive Indication-
Originator Organization
Shanghai Hengrui Pharmaceutical Co., Ltd.Shanghai Hengrui Pharmaceutical Co., Ltd.
Active Organization
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.Shanghai Hengrui Pharmaceutical Co., Ltd.Shanghai Hengrui Pharmaceutical Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)
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Related

4
Clinical Trials associated with SHR-A1912
NCT06104553 / RecruitingPhase 1/2
A Phase Ib/II Study of SHR-A1912 Combined With Other Therapies in Patients With B-cell Non-Hodgkin 's Lymphoma
CTR20233679 / RecruitingPhase 1/2
SHR-A1912联合治疗在B细胞非霍奇金淋巴瘤中的IB/II期研究
[Translation] Phase IB/II Study of SHR-A1912 Combination Therapy in B-Cell Non-Hodgkin Lymphoma
NCT05113069 / Enrolling by invitationPhase 1
A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of SHR-A1912 for Injection as Monotherapy in Patients With B-cell Lymphoma
100 Clinical Results associated with SHR-A1912
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100 Translational Medicine associated with SHR-A1912
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100 Patents (Medical) associated with SHR-A1912
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100 Deals associated with SHR-A1912
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
B-Cell LymphomaPhase 2
CN
Shanghai Hengrui Pharmaceutical Co., Ltd.Shanghai Hengrui Pharmaceutical Co., Ltd.
17 Nov 2023
LymphomaPhase 2
CN
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT05113069 (phase 1 study of SHR-A1912, ASCO2024)
Phase 1
B-Cell Lymphoma
49
nejtyqchns(qmhrzlrfxq) = rdflgpudhq akisiuusvz (mubbgubngn, 39.8 - 71.5)
Positive
24 May 2024
nejtyqchns(qmhrzlrfxq) = ycnridtjhj akisiuusvz (mubbgubngn, 39.8 - 71.5)
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Regulation

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