Last update 22 Aug 2025

BZE-2204

Overview

Basic Info

Drug Type
CAR-T
Synonyms
CD19/​CD22/​BCMA CAR-T(Shanghai Cell Therapy Group), BZE 2204, BZE2204
Target
BCMA x CD19 x CD22
Action
inhibitors
Mechanism
BCMA inhibitors(B-cell maturation protein inhibitors), CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors), CD22 inhibitors(CD22 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication
Relapse multiple myelomaB-cell lymphoma refractoryNon-Hodgkin Lymphoma
Inactive Indication-
Originator Organization
Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
Active Organization
Chantibody Therapeutics, Inc.Chantibody Therapeutics, Inc.Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with BZE-2204
NCT06732232
/ RecruitingEarly Phase 1
A Dose Escalating Study of CD19/CD22/BCMA Three Targets Autologous Chimeric Antigen Receptor T (CAR-T) Cell Therapy in Subjects With Relapsed/Refractory Multiple Myeloma
NCT06446128
/ RecruitingEarly Phase 1
A Dose Escalating Study of CD19/CD22/BCMA Three Targets Autologous Chimeric Antigen Receptor T (CAR-T) Cell Therapy in Subjects With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL)
100 Clinical Results associated with BZE-2204
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100 Translational Medicine associated with BZE-2204
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100 Patents (Medical) associated with BZE-2204
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100 Deals associated with BZE-2204
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Relapse multiple myelomaPhase 1
China
Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
12 Dec 2024
B-cell lymphoma refractoryPhase 1
China
Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
07 May 2024
Non-Hodgkin LymphomaPreclinical
United States
Chantibody Therapeutics, Inc.Chantibody Therapeutics, Inc.
28 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
AACR2025
ManualManual
Not Applicable
Non-Hodgkin's lymphoma refractory | Recurrent Non-Hodgkin Lymphoma
3
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Positive
28 Apr 2025
NEWS
ManualManual
Not Applicable
Diffuse large B-cell lymphoma refractory
1
ppogafnkud(bmlyqhinlc) = dkqpqxxyrx sflpkboecd (mbyedhtxcq )
Positive
27 Dec 2024
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Clinical Trial

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Approval

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Regulation

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