Last update 23 Jan 2025

BZE-2204

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
CD19/​CD22/​BCMA CAR-T(Shanghai Cell Therapy Group)
Target
BCMA x CD19 x CD22
Mechanism
BCMA inhibitors(B-cell maturation protein inhibitors), CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors), CD22 inhibitors(CD22 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesCardiovascular Diseases+ [2]
Active Indication
Relapse multiple myelomaB-cell lymphoma refractory
Inactive Indication-
Originator Organization
Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
Active Organization
Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
Inactive Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with BZE-2204
NCT06732232
/ RecruitingEarly Phase 1
A Dose Escalating Study of CD19/CD22/BCMA Three Targets Autologous Chimeric Antigen Receptor T (CAR-T) Cell Therapy in Subjects With Relapsed/Refractory Multiple Myeloma
NCT06446128
/ Active, not recruitingEarly Phase 1
A Dose Escalating Study of CD19/CD22/BCMA Three Targets Autologous Chimeric Antigen Receptor T (CAR-T) Cell Therapy in Subjects With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL)
100 Clinical Results associated with BZE-2204
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100 Translational Medicine associated with BZE-2204
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100 Patents (Medical) associated with BZE-2204
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100 Deals associated with BZE-2204
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Relapse multiple myelomaPhase 1
CN
Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
12 Dec 2024
B-cell lymphoma refractoryPhase 1
CN
Shanghai Cell Therapy Group Co., Ltd.Shanghai Cell Therapy Group Co., Ltd.
01 Apr 2024
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Clinical Result

Indication
Phase
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Approval

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Regulation

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