Last update 07 Nov 2024

Bulumtatug fuvedotin

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
Anti-nectin-4 IgG1 monoclonal antibody conjugated to monomethyl auristatin E (Mabwell), 9MW 2821, 9MW-2821
+ [1]
Mechanism
Tubulin inhibitors, nectin-4 inhibitors(Nectin-4 inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US), Breakthrough Therapy (CN), Fast Track (US)
Login to view timeline

Structure

Molecular FormulaC39H67N5O7
InChIKeyDASWEROEPLKSEI-UIJRFTGLSA-N
CAS Registry474645-27-7
View All Structures (2)
Boost your research with our XDC technology data.
Boost your research with our XDC technology data.

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Uterine Cervical CancerPhase 3
CN
10 Sep 2024
Transitional Cell CarcinomaPhase 3
CN
29 Dec 2023
Advanced Triple-Negative Breast CarcinomaPhase 2-01 Jul 2024
Metastatic Triple-Negative Breast CarcinomaPhase 2-01 Jul 2024
Advanced Malignant Solid NeoplasmPhase 2
CN
11 Jun 2022
Solid tumorPhase 1
US
29 Jul 2022
Esophageal CarcinomaPreclinical
US
06 May 2024
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
53
pdrfhxsksf(zfyfotqwdq) = qfbqcwodea xfirwcapny (wobubpdlwd )
Positive
23 Aug 2024
(Nectin-4 IHC 3+)
pdrfhxsksf(zfyfotqwdq) = ynxyakjnmt xfirwcapny (wobubpdlwd )
Phase 1/2
240
9MW2821 at 1.25mg/kg or above
(UC)
waocvslxwk(yfthwmfnuf) = axehdgtbab hjptskpbrw (elwsrygjmh, 44.76 - 77.54)
Positive
25 May 2024
9MW2821 at 1.25mg/kg or above
(CC)
waocvslxwk(yfthwmfnuf) = ntspphmynx hjptskpbrw (elwsrygjmh, 23.77 - 53.46)
Phase 1/2
20
xgbfoabolh(meggypszde) = xntshmyhlb cikqtiiygk (fuwgzauajc )
Positive
13 May 2024
Phase 1/2
Uterine Cervical Cancer
NECTIN4 Positive
40
lklirovfke(ngkwjsvods) = bdtcynbvmr hcrfwlbzmf (kuvlcocusq )
Positive
18 Mar 2024
NEWS
ManualManual
Phase 2
-
9MW2821 1.25mg/kg
yzrhevcngz(rsnkdrbngr) = whswzqeahp mjkomcptcj (dngebvvnqj, 44.8 - 77.5)
Positive
07 Dec 2023
Phase 1/2
-
9MW2821
otikfyitlf(kyibkgaudo) = cwkyqqvtji zfxpbkxpxy (xkeksglszv )
Positive
23 Oct 2023
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free