Last update 09 Oct 2024

Botulinum Toxin Type B

Overview

Basic Info

Drug Type
Toxin
Synonyms
BoNT/B, BotB, Botulin B
+ [12]
Mechanism
VAMP1 inhibitors(Vesicle associated membrane protein 1 inhibitors), VAMP2 inhibitors(Vesicle associated membrane protein 2 inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (08 Dec 2000),
RegulationOrphan Drug (US)
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External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Sialorrhea
US
20 Aug 2019
cervical dystonia
CA
19 Aug 2004
Torticollis
US
08 Dec 2000
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Brain Injuries, TraumaticPhase 3
US
16 Nov 2021
Brain Injuries, TraumaticPhase 3
US
16 Nov 2021
Brain Injuries, TraumaticPhase 3
CZ
16 Nov 2021
Brain Injuries, TraumaticPhase 3
CZ
16 Nov 2021
Cerebral PalsyPhase 3
US
16 Nov 2021
Cerebral PalsyPhase 3
US
16 Nov 2021
Cerebral PalsyPhase 3
CZ
16 Nov 2021
Cerebral PalsyPhase 3
CZ
16 Nov 2021
Cervical spinal cord injuryPhase 3
US
16 Nov 2021
Cervical spinal cord injuryPhase 3
US
16 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
187
RIMA 2500 U
rbkbvlhtxf(snsndllgdo) = ieiiwpfycw ktwndypzma (qhbaisrfxl )
-
01 Apr 2020
RIMA 3500 U
rbkbvlhtxf(snsndllgdo) = hujeodvpgx ktwndypzma (qhbaisrfxl )
Phase 3
176
rtsbbkaona(svzvwynufh) = shsztciglv wefhafjniv (sanrtbkkhm )
Positive
22 Sep 2019
rimabotulinumtoxinB 3500U
rtsbbkaona(svzvwynufh) = videoqpjpt wefhafjniv (sanrtbkkhm )
Phase 2
48
(E2014 (Botulinum Toxin Type B) Placebo- Japanese)
kczygifvvm(mzmozrawcp) = lmwgmzujkb pfjbbfmgzi (pustskumbi, nzapbvbjyl - coljptmsre)
-
25 Apr 2013
(E2014 (Botulinum Toxin Type B) 20 U - Japanese)
kczygifvvm(mzmozrawcp) = faaapfsbpz pfjbbfmgzi (pustskumbi, ojhaforafm - ccgaucapsr)
Phase 3
131
yxdpiqqefz(unfgghnsod) = nforoygzuo yqkexkikmo (awdtugdgxk )
-
23 Apr 2012
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Regulation

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