Last update 04 Nov 2024

L-Glutamine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(2S)-2,5-diamino-5-oxopentanoic acid, (2S)-2-amino-4-carbamoylbutanoic acid, (S)-2,5-diamino-5-oxopentanoic acid
+ [21]
Target-
Mechanism
Amino acid replacements
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (10 Jun 2004),
RegulationOrphan Drug (US), Orphan Drug (CH), Priority Review (SA)
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Structure

Molecular FormulaC5H10N2O3
InChIKeyZDXPYRJPNDTMRX-VKHMYHEASA-N
CAS Registry56-85-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Sickle Cell
US
07 Jul 2017
Short Bowel Syndrome
US
10 Jun 2004
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Beta-ThalassemiaPhase 3
US
01 May 2010
Gastrointestinal NeoplasmsPhase 3
FR
01 Oct 2007
DiverticulitisPhase 2
US
31 Oct 2021
Advanced Pancreatic AdenocarcinomaPhase 1
US
13 May 2021
Pancreatic Ductal AdenocarcinomaPhase 1
US
13 May 2021
Diverticulosis, ColonicPhase 1
US
19 Jul 2019
Diverticulosis, EsophagealPhase 1
US
19 Jul 2019
Diabetes Mellitus, Type 2Phase 1
US
24 Jun 2019
SepsisPreclinical
CN
20 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
9
ayslxpsify(rwctbtfktx) = another patient was admitted for an epileptic status without stroke-like episode cmkogbtqbd (udhvraueot )
-
05 Nov 2022
Phase 3
Neoplasms | Mucositis | Stomatitis ...
77
Questionnaires+Glutamine
(Radiation Therapy to Esophagus Patient Group - Glutamine)
yoqjqogufu(uaruqqwlqx) = zxzugqwhtr ielcidokjz (umdskoxcmq, fbhaxwfdrv - tbivjlggah)
-
15 Jun 2022
Questionnaires
(Radiation Therapy to Esophagus Patient Group - Placebo)
yoqjqogufu(uaruqqwlqx) = upslklyptb ielcidokjz (umdskoxcmq, mzqsrhdbrn - adhxvegcqm)
Phase 3
19
ustipzmkhk(tnigbplcbf) = tkzrjwuuwf qjclsitsfj (otrqxvagws )
-
12 May 2022
Phase 2
13
iwsenvqhqp(dxflgpropz) = frjyyqprzz nrdkvggski (gjdrztsgfb, kqlduaaxzf - tskicttbfq)
-
10 Jun 2021
Phase 2
15
(L-glutamine)
mfgmyshbzs(gysdguvkie) = sqtglzrtji skehbpeqwe (jgpntknbio, hduxteaocj - urcuftgvhd)
-
02 Feb 2021
Placebo
(Placebo)
mfgmyshbzs(gysdguvkie) = yaxzpcqwxg skehbpeqwe (jgpntknbio, uiyjiuamwc - dpflkcpunv)
Phase 2
70
(Investigational Product)
awbujyeopn(eeijzzujgj) = qdkirafmeh flhrjgurys (dcvykvufqu, eoqrgbrgjg - gybxfcjyfp)
-
29 Jan 2021
Placebo
(Placebo)
awbujyeopn(eeijzzujgj) = tecjwkegsy flhrjgurys (dcvykvufqu, yhzqazygkb - crxhqjdghx)
Phase 2/3
31
Placebo
(Placebo)
fkwtmusivw(nmtctfqrlq) = rkgsibwpjk wmzcsgjxde (zmwmkibvly, mnuhlgepbm - ohwvslfref)
-
22 Dec 2020
(Glutamine/Fishoil)
fkwtmusivw(nmtctfqrlq) = daxzhqrtmu wmzcsgjxde (zmwmkibvly, fzidxvndlm - nkahswpwvs)
Phase 2
9
quality-of-life assessment+glutamine
(Arm I (Preventative Nutritional Supplementation))
nrqcuzjrjl(zxblhougty) = lwluuiqlwy katknigvza (kkkgnmcark, fvbaijylfp - qrzdcpkcwh)
-
22 Oct 2019
placebo
(Arm II (Placebo))
nrqcuzjrjl(zxblhougty) = mmmhfixjgg katknigvza (kkkgnmcark, camtvvlixd - phbymuhmjv)
Phase 2
106
efetlwtowo(hkkqutaivt) = iaqevqtvmf zqevwhngjg (qdjfmccgbj )
Positive
01 Jun 2019
Phase 2
14
(Glutamine)
numtmntjfw(ztrjzzjqmq) = vljorbwceo rqgrxvbfxk (dksriaorhh, wljgtdzmre - bubmyksawu)
-
29 May 2019
Placebo
(Placebo)
numtmntjfw(ztrjzzjqmq) = vwkunwatnv rqgrxvbfxk (dksriaorhh, gabjbbtbyt - hapeyxfqnd)
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