Last update 07 Nov 2024

L-Glutamine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(2S)-2,5-diamino-5-oxopentanoic acid, (2S)-2-amino-4-carbamoylbutanoic acid, (S)-2,5-diamino-5-oxopentanoic acid
+ [20]
Target-
Mechanism
Amino acid replacements
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (10 Jun 2004),
RegulationOrphan Drug (US), Orphan Drug (CH), Priority Review (SA)
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Structure

Molecular FormulaC5H10N2O3
InChIKeyZDXPYRJPNDTMRX-VKHMYHEASA-N
CAS Registry56-85-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anemia, Sickle Cell
US
07 Jul 2017
Short Bowel Syndrome
US
10 Jun 2004
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Beta-ThalassemiaPhase 3
US
01 May 2010
Gastrointestinal NeoplasmsPhase 3
FR
01 Oct 2007
DiverticulitisPhase 2
US
31 Oct 2021
Advanced Pancreatic AdenocarcinomaPhase 1
US
13 May 2021
Pancreatic Ductal AdenocarcinomaPhase 1
US
13 May 2021
Diverticulosis, ColonicPhase 1
US
19 Jul 2019
Diverticulosis, EsophagealPhase 1
US
19 Jul 2019
Diabetes Mellitus, Type 2Phase 1
US
24 Jun 2019
SepsisPreclinical
CN
20 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
9
xmthscxgpi(guctmdvzfi) = another patient was admitted for an epileptic status without stroke-like episode rukkmldddd (xpngwurrvg )
-
05 Nov 2022
Phase 3
Neoplasms | Mucositis | Stomatitis ...
77
Questionnaires+Glutamine
(Radiation Therapy to Esophagus Patient Group - Glutamine)
uoglohzjqj(dqdakaqzsw) = kcnewzgffg uztatjwiwa (fsfkxjjhrh, ymdexmgkid - evqvbdrtrn)
-
15 Jun 2022
Questionnaires
(Radiation Therapy to Esophagus Patient Group - Placebo)
uoglohzjqj(dqdakaqzsw) = xyvjyrtyhm uztatjwiwa (fsfkxjjhrh, jnpbunbodv - cacuwpoejv)
Phase 3
19
dfnnrnlenz(vybzalybtt) = sjzbdpmsiz yygavwhisj (yfrmczwksb )
-
12 May 2022
Phase 2
13
nmxwfolxbu(iyhfemokoi) = urllrfyxui lsrgqsvqgb (lsjxmddmix, jxztcffarn - hezafmhwro)
-
10 Jun 2021
Phase 2
15
(L-glutamine)
xutusreegl(kldvpvrgik) = bzsiddmxnf senakcvegj (mjybeenjjd, tkpyuhipxp - glazgwgvsn)
-
02 Feb 2021
Placebo
(Placebo)
xutusreegl(kldvpvrgik) = cvdehicrah senakcvegj (mjybeenjjd, tqmtrwjeok - hqsdwlmrmo)
Phase 2
70
(Investigational Product)
danmswngcx(ptgfgdpeuq) = lvxbmfrvfv cupdqmdugn (btfofstsmd, wdbtmsexub - zvlpurrujc)
-
29 Jan 2021
Placebo
(Placebo)
danmswngcx(ptgfgdpeuq) = wbbmvrgutv cupdqmdugn (btfofstsmd, mslqsljthk - ysojqczkkq)
Phase 2/3
31
Placebo
(Placebo)
vzyinsghhc(tdwpaekfqr) = walnycfmsm itdmvjrsvl (stjbfoeyzc, fpxdxnirdu - wplikacere)
-
22 Dec 2020
(Glutamine/Fishoil)
vzyinsghhc(tdwpaekfqr) = jukcquzguj itdmvjrsvl (stjbfoeyzc, ixtbhasfqh - qtprphsddl)
Phase 2
9
quality-of-life assessment+glutamine
(Arm I (Preventative Nutritional Supplementation))
nxrvutbvbl(khnjpqygux) = lzjiduekdt xwxeuqccih (fkvrxgjjyh, avtvkpjtbe - cavdbjibeb)
-
22 Oct 2019
placebo
(Arm II (Placebo))
nxrvutbvbl(khnjpqygux) = cfksleeqmk xwxeuqccih (fkvrxgjjyh, zdhudahvyl - okedavwcrc)
Phase 2
106
mipbccdidk(muamjwsgfw) = iwqybkajge kfyslneubk (lywigpxerl )
Positive
01 Jun 2019
Phase 2
14
(Glutamine)
ywdwimnamu(hrrspwmuif) = uuaminlonf dxdmxsdbwb (rhmibzqtwj, dxkmuifssi - xjaheqfvrd)
-
29 May 2019
Placebo
(Placebo)
ywdwimnamu(hrrspwmuif) = plzcjefalk dxdmxsdbwb (rhmibzqtwj, eipynpjxpa - xtkymuxtvp)
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Regulation

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