Last update 07 Nov 2024
APS03118
Last update 07 Nov 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms APS 03118, APS-03118 |
Target |
Mechanism RET inhibitors(Tyrosine-protein kinase receptor RET inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
RegulationFast Track (US) |
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Related
2
Clinical Trials associated with APS03118A Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of APS03118 in Adult Patients With Unresectable Locally Advanced or Metastatic Solid Tumors Harboring RET Mutations or Fusions
一项在携带RET突变或融合的不可切除、局部晚期或转移性实体瘤成人患者中研究APS03118的安全性、耐受性、药代动力学和初步疗效的I期研究
[Translation] A Phase I study investigating the safety, tolerability, pharmacokinetics, and preliminary efficacy of APS03118 in adult patients with unresectable, locally advanced, or metastatic solid tumors harboring RET mutations or fusions
100 Clinical Results associated with APS03118
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100 Translational Medicine associated with APS03118
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100 Patents (Medical) associated with APS03118
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100 Deals associated with APS03118
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 1 | CN | 06 Feb 2023 | |
| RET mutation Solid Tumors | Phase 1 | CN | 17 Nov 2022 | |
| Breast Cancer | Phase 1 | US | 30 Jan 2022 | |
| Breast Cancer | Phase 1 | CN | 30 Jan 2022 | |
| Colorectal Cancer | Phase 1 | US | 30 Jan 2022 | |
| Colorectal Cancer | Phase 1 | CN | 30 Jan 2022 | |
| Non-Small Cell Lung Cancer | Phase 1 | US | 30 Jan 2022 | |
| Thyroid Cancer | Phase 1 | US | 30 Jan 2022 | |
| Thyroid Cancer | Phase 1 | CN | 30 Jan 2022 |
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