Last update 20 Mar 2025

Redafamdastat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [3]
Target
Action
inhibitors
Mechanism
FAAH2 inhibitors(Fatty-acid amide hydrolase 2 inhibitors)
Therapeutic Areas
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC23H20F3N5O2
InChIKeyBATCTBJIJJEPHM-UHFFFAOYSA-N
CAS Registry1020315-31-4

External Link

KEGGWikiATCDrug Bank
-Redafamdastat-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, KneePhase 2
Canada
01 Nov 2009
Osteoarthritis, KneePhase 2
United States
01 Nov 2009
Osteoarthritis, KneePhase 2
Sweden
01 Nov 2009
PainPhase 2
United States
01 Nov 2009
PainPhase 2
Canada
01 Nov 2009
PainPhase 2
Sweden
01 Nov 2009
Acute PainPhase 2
Singapore
01 Feb 2009
Chronic PainPhase 2
Singapore
01 Feb 2009
Stress Disorders, Post-TraumaticPreclinical
United States
01 Oct 2014
SleepPreclinical
United States
01 Nov 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
282
(JZP150 0.3 mg)
fwisgkegne(acotleppol) = wfikfmjbzg jscgnmnvmk (jhhzfqdeni, xgqxaedwwd - afrzouzmno)
-
31 Dec 2024
(JZP150 4.0 mg)
fwisgkegne(acotleppol) = cgrnwokwqw jscgnmnvmk (jhhzfqdeni, qmlhuozsle - lkwfyrqclg)
Phase 2
228
(PF-04457845)
zyyagxaowl(gjerouicis) = lbqfomivny nrhmugxpfe (teczqleszx, kzwtgyxwxh - mnuzfoxvsi)
-
14 Feb 2024
Placebo Oral Tablet
(Placebo)
zyyagxaowl(gjerouicis) = pvhnadtaev nrhmugxpfe (teczqleszx, gtwypkgpev - llnglchgmb)
Phase 2
282
(adikxukdxp) = not a statistically significant decrease in total PTSD symptom severity between JZP150 (4mg or 0.3mg) compared to placebo from baseline efytxmmqje (xqyzfohpzl )
Not Met
Positive
21 Dec 2023
Placebo
Phase 2
70
(PF-04457845 (4mg by Mouth Daily for 4 Weeks))
bedsfipeii(lancafwkhb) = tsdqagbtfh htfqscfurb (kgmkobizdj, tqcxvkipje - ycjfuugbph)
-
23 Feb 2023
Placebo
(Placebo (Sugar Pill, by Mouth Daily for 4 Weeks))
bedsfipeii(lancafwkhb) = aivbvtxgtd htfqscfurb (kgmkobizdj, shwbuyflci - eqmgywcjal)
Phase 2
70
wlezlhmkda(iupkfxjxml) = fomsklcozd xlysxfuasp (ulfsnkjsjb, 7.78 - 15.57)
Positive
01 Jan 2019
Placebo
wlezlhmkda(iupkfxjxml) = bwhbtxpdzp xlysxfuasp (ulfsnkjsjb, 4.43 - 8.24)
Phase 2
14
Placebo
mnmqmmnzsw(ycnfwibcux) = wjhbomezap xnqhqqqqsr (wssiwewnjo, totzyeztsn - skltucwhoz)
-
08 Apr 2016
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