Last update 07 Nov 2024

SPL-108

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
Mechanism
CD44 inhibitors(CD44 antigen inhibitors)
Active Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ovarian CancerPhase 2--
Platinum-Resistant Epithelial Ovarian CarcinomaPhase 1
US
10 Mar 2017
Endometrial CarcinomaPreclinical
US
29 Jul 2018
Liver CancerPreclinical
US
13 Jul 2018
Brain CancerPreclinical
US
09 Jul 2018
Breast CancerPreclinical
US
09 Jul 2018
Dystrophy, MacularPreclinical
US
08 Apr 2018
Rheumatoid ArthritisPreclinical
US
07 Apr 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
14
SPL-108 + Paclitaxel
iniooqmagr(eserbzstke) = One patient had grade 3 peripheral sensory neuropathy attributed to paclitaxel ajaclydqtt (dqwbnistar )
Positive
24 Jun 2022
Phase 1
Ovarian Cancer
CD44 Positive
14
paclitaxel+SPL-108
cydivsfazi(emrijktono) = ypsqdtfpyy duuwnqurye (flzafgivob )
Positive
29 May 2020
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Regulation

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