Last update 19 Sep 2024

ONC-206

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mechanism
CLPP agonists(caseinolytic mitochondrial matrix peptidase proteolytic subunit agonists), D2 receptor antagonists(Dopamine D2 receptor antagonists), D3 receptor antagonists(Dopamine D3 receptor antagonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-

Structure

Molecular FormulaC23H22F2N4O
InChIKeyITMGVSSHWMTJRR-UHFFFAOYSA-N
CAS Registry1638178-87-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Choroid Plexus NeoplasmsPhase 1
US
26 Oct 2020
Diffuse AstrocytomaPhase 1
US
26 Oct 2020
Diffuse midline glioma, point mutation K27M in histone H3Phase 1
US
26 Oct 2020
EpendymomaPhase 1
US
26 Oct 2020
GlioblastomaPhase 1
US
26 Oct 2020
GliosarcomaPhase 1
US
26 Oct 2020
MedulloblastomaPhase 1
US
26 Oct 2020
PinealomaPhase 1
US
26 Oct 2020
Typical Teratoid Rhabdoid TumorPhase 1
US
26 Oct 2020
GangliogliomaDiscovery
US
26 Oct 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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