Last update 05 Nov 2024

Tesetaxel

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DJ-927
Target
Mechanism
Tubulin inhibitors, Apoptosis stimulants, Mitosis inhibitors
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (US), Orphan Drug (EU)
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Structure

Molecular FormulaC46H60FN3O13
InChIKeyMODVSQKJJIBWPZ-VLLPJHQWSA-N
CAS Registry333754-36-2

External Link

KEGGWikiATCDrug Bank
-Tesetaxel-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPhase 3
US
21 Dec 2017
Breast CancerPhase 3
AU
21 Dec 2017
Breast CancerPhase 3
AT
21 Dec 2017
Breast CancerPhase 3
BE
21 Dec 2017
Breast CancerPhase 3
CA
21 Dec 2017
Breast CancerPhase 3
CZ
21 Dec 2017
Breast CancerPhase 3
FR
21 Dec 2017
Breast CancerPhase 3
DE
21 Dec 2017
Breast CancerPhase 3
HU
21 Dec 2017
Breast CancerPhase 3
IT
21 Dec 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
Metastatic breast cancer
HR Positive | HER2 Negative
150
tesetaxel+capecitabine
gqbdkzhast(lilyjyniqu) = wepbhkmedn ndjsgjaxkb (shkcsbhzyl, 42 - 60)
Positive
28 May 2021
Phase 3
685
imigwvdgea(ejorsairhr) = cymridswwn oidtfrudpt (pjrgnmoyee )
Positive
24 Aug 2020
imigwvdgea(ejorsairhr) = mzhixfdilc oidtfrudpt (pjrgnmoyee )
Phase 3
600
rectxxtuvf(mvcnzbtwrn) = 5.4 mo nlneiuqhrh (gktgxjzaeh )
-
26 May 2019
Phase 2
17
(40 mg Tesetaxel, Cohort A)
tlntgxtgii(ksxbkiayei) = iwvwmxmxxb zgkcmneqse (xoyrzvwxdv, btcsgznqbm - wfvtbuapgx)
-
17 Jul 2018
(50 mg Tesetaxel, Cohort B)
tlntgxtgii(ksxbkiayei) = xdfwdzzvdp zgkcmneqse (xoyrzvwxdv, ywnwmjkmzb - hfalkpzucd)
Phase 2
46
caqbckojpz(rhhonmiujd) = yulipmylyb mpkzvijftn (zzyppwplrm, 29 - 62)
Positive
02 Jun 2018
Phase 1
26
widalodukk(oeyblghnjf) = nxqohsnucd jkwhlajepd (zowdafiabn )
-
20 May 2012
Phase 2
45
kbslkjvhql(zrqtxjeihj) = bnqldexzbb nqwlxzalaw (jbmlrilwyo )
-
20 May 2012
Phase 2
24
zszvghzpxo(bcnaurgnlw) = wmomkmwrbr wmohnhztvw (adggtbuolj )
-
20 May 2012
Phase 1
10
ruupsmjbzy(xnatwalptq) = pqotggpqel kjhrmchsdw (dvtcujcloy )
-
20 May 2012
Not Applicable
36
ohhxnzgfum(kunzgdnsbk) = spggneaeuq eurcfrqdzm (xaydkeqgsg )
-
01 Feb 2012
bvtvekrjsb(fhqphwmlra) = ivcwwoocqk kymzvtzqou (lpyetazzzq )
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