Last update 21 Nov 2024

ACE-86225106

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
PARP1
Mechanism
PARP1 inhibitors(Poly (ADP-Ribose) polymerase 1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid NeoplasmAdvanced cancerNeoplasms
Inactive Indication-
Originator Organization
Acerand Therapeutics (Shanghai) Co., Ltd.
Active Organization
Acerand Therapeutics (Shanghai) Co., Ltd.Acerand Therapeutics
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with ACE-86225106
NCT06380660 / RecruitingPhase 1/2
A Phase I/II, Open-label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Ascending Doses of ACE-86225106 as Monotherapy in Patients With Advanced Solid Tumors
CTR20240158 / RecruitingPhase 1/2
一项在晚期实体瘤患者中评估ACE-86225106递增剂量单药治疗安全性、耐受性、药代动力学、药效学和初步疗效的开放性、多中心I/II期研究
[Translation] An open-label, multicenter, Phase I/II study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of ACE-86225106 as a monotherapy in patients with advanced solid tumors
100 Clinical Results associated with ACE-86225106
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100 Translational Medicine associated with ACE-86225106
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100 Patents (Medical) associated with ACE-86225106
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100 Deals associated with ACE-86225106
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
CN
Acerand Therapeutics (Shanghai) Co., Ltd.
07 Mar 2024
Advanced cancerIND Approval
CN
Acerand Therapeutics (Shanghai) Co., Ltd.
06 Nov 2023
NeoplasmsDiscovery
US
Acerand Therapeutics
22 Mar 2024
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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