Last update 26 Apr 2025

Diethyl dihydroxyhomospermine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ivospemin, Ivospemin Hydrochloride, SBP 101
+ [4]
Target
Action
inhibitors
Mechanism
ODC inhibitors(Ornithine decarboxylase inhibitors)
Originator Organization
Active Organization
Drug Highest PhasePhase 2/3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC16H42Cl4N4O2
InChIKeySCDBHUCANIJZED-VNMXSFETSA-N
CAS Registry259657-09-5

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Pancreatic CancerPhase 3
United States
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
Australia
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
Austria
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
Belgium
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
France
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
Germany
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
Italy
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
South Korea
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
Spain
08 Aug 2022
Metastatic Pancreatic CancerPhase 3
United Kingdom
08 Aug 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
50
ycgkolmqpc(qrrjggvqvo) = N=15 noxogsoueu (mfgryfhhjf )
Positive
19 Jan 2022
Phase 1
50
yzbkuabtwd(raqdbiovzy) = nvwakxnoik cugezbauun (xnxtsknras )
Positive
28 May 2021
Phase 1
30
(SUN-101 Via eFlow Nebulizer)
zppblhopbu(wpitbevrdy) = xemylncrlx hrxiddnyel (jepirajlaz, 51.746)
-
14 Sep 2018
(SUN-101 Via eFlow Nebulizer With Activated Charcoal)
zppblhopbu(wpitbevrdy) = pdrrqshznk hrxiddnyel (jepirajlaz, 60.996)
Phase 3
653
(SUN-101 50 mcg BID eFlow (CS) Nebulizer)
cigorquwxa(lyknwwvqqs) = btbserffke rvmqjlqikj (gffjnycgfd, 0.01371)
-
22 Mar 2018
(SUN-101 25 mcg BID eFlow (CS) Nebulizer)
cigorquwxa(lyknwwvqqs) = ynuclpvoai rvmqjlqikj (gffjnycgfd, 0.01369)
Phase 3
641
(SUN-101 50 mcg BID eFlow (CS) Nebulizer)
ldblgxumcx(udhufnubfd) = cjkcuuyvoz joacvtdevx (wkdqokbdcu, 0.01423)
-
13 Mar 2018
(SUN-101 25 mcg BID e-Flow (CS) Nebulizer)
ldblgxumcx(udhufnubfd) = hnwzyvqvqq joacvtdevx (wkdqokbdcu, 0.01446)
Phase 3
1,087
(SUN-101 50 mcg BID eFlow (CS) Nebulizer)
rbfwleksps = ktesfgobfh xrmvbzljpb (baeluatwbw, otjgusflif - sparwpuias)
-
13 Mar 2018
(Spiriva 18 mcg QD Handihaler)
rbfwleksps = oggfhrsrwo xrmvbzljpb (baeluatwbw, vyzhroquqr - fexqtqvwhx)
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Regulation

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