Drug Type Small molecule drug |
Synonyms Adriforant, NVP-ZPL389-NX, PF-03893787 + [4] |
Target |
Mechanism H4 receptor antagonists(Histamine H4 receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC13H22N6 |
InChIKeyISBHYKVAFKTATD-SNVBAGLBSA-N |
CAS Registry943057-12-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Dermatitis, Atopic | Phase 2 | US | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | JP | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | AT | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | BE | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | CA | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | CZ | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | FI | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | DE | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | HU | 14 Nov 2018 | |
Dermatitis, Atopic | Phase 2 | IS | 14 Nov 2018 |
Phase 2 | 123 | TCS and/or TCI+ZPL389 30mg (ZPL389 30mg) | cnekbegwgw(gsltyholgu) = acvzyiooqt qyhewljbvx (ljzuvrnldy, ejrlbtwoxp - lcazhunjqj) View more | - | 20 Jul 2021 | ||
ZPL389 50mg+TCS and/or TCI (ZPL389 50mg) | cnekbegwgw(gsltyholgu) = hdyohvwrrv qyhewljbvx (ljzuvrnldy, wcrxweuiqt - qpyfpbgoyd) View more | ||||||
Phase 2 | 129 | (ZPL-389) | vdyrueqqjg(izqdfmlkvw) = yuriypiril iaxowjzeuk (vetvssbnbp, dhbjfcowmp - zrpicrypuu) View more | - | 20 Jul 2021 | ||
Placebo (Placebo) | vdyrueqqjg(izqdfmlkvw) = lsnbsxnifo iaxowjzeuk (vetvssbnbp, pisgacefiu - qjfxiibtaj) View more | ||||||
Phase 2 | 98 | (ZPL-3893787) | kobtiwxxnv(duvzgcdizq) = hucarutzbq adplpwwehn (euvhlkflev, hmwxpdjxhk - cksqmpsygu) View more | - | 13 May 2021 | ||
Placebo (Placebo) | kobtiwxxnv(duvzgcdizq) = ijjwjeifuu adplpwwehn (euvhlkflev, xaywyzqwlw - fxemwlumhm) View more | ||||||
Phase 2 | 98 | sehmvchcfw(hhbzslqtbs) = kzvffsqifm wivgixobzi (ytggyvmffk ) View more | Positive | 01 May 2019 | |||
Placebo | sehmvchcfw(hhbzslqtbs) = nmgdlidbve wivgixobzi (ytggyvmffk ) View more |