Last update 03 Sep 2025

COVID-19 Vaccine (ChAdOx1-S [recombinant])(AstraZeneca Plc)

Overview

Basic Info

Drug Type
Recombinant vector vaccine, Prophylactic vaccine
Synonyms
ChAdOx1 nCoV-19, ChAdOx1-S, ChAdOx1-S (Recombinant)
+ [8]
Action
inhibitors
Mechanism
SARS-CoV-2 S protein inhibitors(SARS-CoV-2 S protein inhibitors)
Active Indication
Inactive Indication
Drug Highest PhaseApproved
First Approval Date
United Kingdom (30 Dec 2020),
RegulationEmergency Use Authorization (Japan)
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
COVID-19
United Kingdom
30 Dec 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 2
South Africa
24 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
172
jbgafxeyux(plolvpveys) = jlqoujprra zuqhlhjusp (nqxzltqkit, 1.6 - 2.4)
Positive
01 Aug 2025
Phase 4
34
(Immunocompromised Cohort)
jsfbiikush(wnrwsirhgp) = jyigxkqmvq rmqxqwxcqs (vqmvetdegn, enyjzubtyd - kfojlzfand)
-
27 Jan 2025
(Immunocompetent Cohort)
jsfbiikush(wnrwsirhgp) = frxwsgodyo rmqxqwxcqs (vqmvetdegn, nutkvaftuz - jamhnsvuih)
Phase 1/2
256
(Cohort C: AZD1222)
jekwuzkupc = vwxgtpsjco ylnzktzjko (vuiwjynoel, rmgghduism - mbmwndugwh)
-
01 Mar 2024
placebo+AZD1222
(Cohort C: Placebo)
jekwuzkupc = qywbbaqpwx ylnzktzjko (vuiwjynoel, ygdfbwxyil - etakoesyap)
Not Applicable
anti-RBD antibody titers
36
ftbzhsxxhe(khgbgugoty) = one serious adverse event not related to vaccination occurred mxikhrnran (wbttkbvpxa )
Negative
13 Nov 2022
Not Applicable
130
Inactivated Vaccine
(Sinovac (SV-SV))
untetbgooz(mbaftlqrjn) = tugzayalpr bbapjxsrsq (csdskhnaie )
Positive
03 Nov 2022
AZD1222 (AZ-AZ)
untetbgooz(mbaftlqrjn) = poycktotqz bbapjxsrsq (csdskhnaie )
Phase 3
32,450
mvxdbcprmk(ifxyhqhdih) = lsomrzzkdx pcmwbrkblo (nlkbfvdgbo )
Positive
15 Sep 2022
Placebo
mvxdbcprmk(ifxyhqhdih) = juenjfgvhq pcmwbrkblo (nlkbfvdgbo )
Not Applicable
-
2nd dose AZD1222
rljtrngmuq(zvhslkavus) = Three catastrophic cases including 2 fatalities occurred. Concomitant factors were present in all and influenced outcome severity. jikvxhurny (aeexpbcsdi )
-
09 Jul 2022
Not Applicable
399
(Solid malignancy patients on active cancer treatment)
oeyjjjhtea(yhqcofspba) = rmdfffynrd ixokcovrsp (ktjmmnckzq )
Positive
02 Jun 2022
(Healthy controls)
oeyjjjhtea(yhqcofspba) = adaixkdrjm ixokcovrsp (ktjmmnckzq )
Not Applicable
-
Hold MTX after each dose of ChAdOx1 vaccine
pvlogjgxhm(ccxrawrpce) = dklogdsadw ioxntqbeno (boecovspkl )
-
01 Jun 2022
Continue MTX after each dose of ChAdOx1 vaccine
pvlogjgxhm(ccxrawrpce) = gmiuyfgcoo ioxntqbeno (boecovspkl )
Not Applicable
11
AZD1222 COVID-19 mRNA vaccine
ftmbfoxfdc(jtdqdwkifr) = two patients developed VZV after the first dose of 253 Pfizer vaccine and both were proceeded to the second dose of vaccine without any complications spfofhwqmn (ehyvygzlcu )
Positive
12 May 2022
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Core Patent

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Clinical Trial

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Approval

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Regulation

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