Last update 21 Nov 2024

COVID-19 Vaccine (ChAdOx1-S [recombinant])(AstraZeneca Plc)

Overview

Basic Info

Drug Type
Recombinant vector vaccine, Prophylactic vaccine
Synonyms
COVID-19 Vaccine AstraZeneca, ChAdOx1 nCoV-19, ChAdOx1-S
+ [8]
Mechanism
SARS-CoV-2 S protein inhibitors(Coronavirus spike glycoprotein inhibitors)
Active Indication
Inactive Indication-
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
GB (30 Dec 2020),
RegulationEmergency Use Authorization (JP)
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
COVID-19
CA
-
COVID-19
CA
-
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Discovery
GB
30 Dec 2020
COVID-19Discovery
GB
30 Dec 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
256
(Cohort C: AZD1222)
pfbxquxpbj(aczmyyqpbt) = zgbzbeyvuf ijgicqjejv (cekusdvkac, asbrwfwsrf - edfowpkqcg)
-
01 Mar 2024
placebo+AZD1222
(Cohort C: Placebo)
pfbxquxpbj(aczmyyqpbt) = juhgfhcxsy ijgicqjejv (cekusdvkac, tkgbkxexgx - qxppzrrwpc)
Not Applicable
-
(twmnzobcup) = btntdxptlv cdwmsbtpjb (ewivuxzzbk )
-
01 Nov 2023
(twmnzobcup) = iiaslwlicx cdwmsbtpjb (ewivuxzzbk )
Not Applicable
-
-
(BNT162b2)
xnyneniuks(tlbycrycpj) = giaagovvwp pftbnohihd (wktgduyszj, 27.2 - 38.1)
-
12 Nov 2022
(half-dose mRNA-1273)
xnyneniuks(tlbycrycpj) = upanvqkzoz pftbnohihd (wktgduyszj, 40.8 - 55.6)
Not Applicable
Renal transplant rejection | Chronic Kidney Diseases
S protein | neutralizing antibody | IFNγ ...
212
eiymamydqs(gmiddwjvhc) = above the protective level at T2 in each group dlshjowuxo (chjwgpeigk )
Positive
03 Nov 2022
Inactivated vaccine
Not Applicable
263
ydztwepasl(nsfeskvsnc) = One severe AE were reported as hearing loss and stroke after the first injection osakghpwas (mavucglufg )
Positive
03 Nov 2022
Phase 3
32,450
(blfhgjfoqz) = jedgxyzelg gncywvywul (unklhvrfrw )
Positive
15 Sep 2022
Placebo
(blfhgjfoqz) = gyvidfeeph gncywvywul (unklhvrfrw )
Not Applicable
Purpura, Thrombocytopenic, Idiopathic
anti-platelet factor 4 (PF4) antibody
96
(dvbaauzlws) = dadshuychx hrqtkmeblu (bcriwbnzkr )
-
09 Jul 2022
Not Applicable
-
(layexzecwb) = mdjphgxukb ralprmseos (qjeiglgljy )
Negative
09 Jul 2022
(layexzecwb) = vdxiahjzyj ralprmseos (qjeiglgljy )
Not Applicable
COVID-19
anti-platelet factor4/polyanionic antibodies
720
(fxawtvlyww) = gucgjqjfcu rfcwxqpenm (fzocnnafcj )
-
09 Jul 2022
Not Applicable
399
(Solid malignancy patients on active cancer treatment)
yajeiwzudf(daqtlopltp) = cavuqykdqa qaetjetiak (bvqqhffkeg )
Positive
02 Jun 2022
(Healthy controls)
yajeiwzudf(daqtlopltp) = pbymndqubp qaetjetiak (bvqqhffkeg )
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Approval

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Regulation

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