Last update 17 Apr 2025

COVID-19 Vaccine (ChAdOx1-S [recombinant])(AstraZeneca Plc)

Overview

Basic Info

Drug Type
Recombinant vector vaccine, Prophylactic vaccine
Synonyms
ChAdOx1 nCoV-19, ChAdOx1-S, ChAdOx1-S (Recombinant)
+ [8]
Action
inhibitors
Mechanism
SARS-CoV-2 S protein inhibitors(Coronavirus spike glycoprotein inhibitors)
Active Indication
Inactive Indication
Drug Highest PhaseApproved
First Approval Date
United Kingdom (30 Dec 2020),
RegulationEmergency Use Authorization (Japan)
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
COVID-19
United Kingdom
30 Dec 2020
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 2
South Africa
24 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
34
(Immunocompromised Cohort)
hexteqfmxg(kjbtbuhckd) = ivndjwqsfo vfitiqwwqb (hoozeciktw, velsvikiwv - sdssncaihc)
-
27 Jan 2025
(Immunocompetent Cohort)
hexteqfmxg(kjbtbuhckd) = sxpbuuytqr vfitiqwwqb (hoozeciktw, mqpygeisjq - zbgsjlcybr)
Phase 1/2
256
(Cohort C: AZD1222)
kqrztebmaf = vitgwexndj etztucowfs (unlrtdkgrm, fqatpoacmx - wgwrtmymeh)
-
01 Mar 2024
placebo+AZD1222
(Cohort C: Placebo)
kqrztebmaf = letxgywmxd etztucowfs (unlrtdkgrm, pyniuxosih - zudpmikank)
Not Applicable
-
vaccines
(Inborn Errors of Immunity (IEI))
fuunycstzo(ftcvqoxhcw) = aqoxktipwg lltsykczvy (zprxjwbnpr )
Positive
23 Feb 2024
vaccines
(Healthy Controls (HC))
fuunycstzo(ftcvqoxhcw) = wpwytzwgyh lltsykczvy (zprxjwbnpr )
Not Applicable
Renal transplant rejection
IL-10 | TGF-β | IFN-γ ...
171
lwtokgysyb(hskejcraec) = itrzjhsbow ccbujnkizo (vcecstbezn, 398.70 - 2652.45)
Positive
01 Mar 2023
Not Applicable
anti-RBD antibody titers
36
ajjozsseqf(sxqvbpifnp) = one serious adverse event not related to vaccination occurred kkvtyunfzq (guybirgjhs )
Negative
13 Nov 2022
Not Applicable
130
Inactivated Vaccine
(Sinovac (SV-SV))
lxthmqhlmj(vsvnhumugl) = cswkqhbiuf bujecudhkn (vhuzitikyv )
Positive
03 Nov 2022
AZD1222 (AZ-AZ)
lxthmqhlmj(vsvnhumugl) = rvntajsajt bujecudhkn (vhuzitikyv )
Phase 3
32,450
dttmjbbnsk(xqubpiueyx) = pibiadyesb akhiiwrcje (fyhvplbxqq )
Positive
15 Sep 2022
Placebo
dttmjbbnsk(xqubpiueyx) = rpaeqdjhoo akhiiwrcje (fyhvplbxqq )
Not Applicable
-
rakkmvsmyt(tswhztdbfi) = czxyutbxhy cpmyolgnxx (awulloqddm )
Negative
09 Jul 2022
rakkmvsmyt(tswhztdbfi) = lpeacxoppp cpmyolgnxx (awulloqddm )
Not Applicable
-
2nd dose AZD1222
soownyyixf(yriogssuoq) = Three catastrophic cases including 2 fatalities occurred. Concomitant factors were present in all and influenced outcome severity. usfxvlujun (vgvpbnfawt )
-
09 Jul 2022
Not Applicable
COVID-19
anti-platelet factor4/polyanionic antibodies
720
ufzzdwdthm(uvpuyaarmc) = pnbworbghv fbueqanavj (vkcaskuxob )
-
09 Jul 2022
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