Last update 08 Nov 2024

Levilimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Ilsira, BCD-089
Target
Mechanism
IL-6RA antagonists(Interleukin-6 receptor alpha subunit antagonists)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RU (04 Jun 2020),
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Rheumatoid Arthritis
RU
08 Jun 2021
COVID-19
RU
04 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
154
hydencehjv(carngvctmy) = bzlniynjuv wgufzieuuj (wmopukbtuq )
Positive
01 Jun 2022
Phase 3
217
kuarmvuuay(gesrqvsxwl) = ltdsiuvnqs gdtxtdrhdz (dscaafoemq )
Positive
01 Dec 2021
Placebo+SOC
kuarmvuuay(gesrqvsxwl) = jcfbmrrmca gdtxtdrhdz (dscaafoemq )
Phase 3
COVID-19
Erythrocyte sedimentation rate (ESR) | C-reactive protein (CRP) | IL-6
217
hgjlbttynq(vynoglexip) = tgzssfbcwk pviqvgqzyd (okmuetiglr )
Positive
02 Jun 2021
Placebo
hgjlbttynq(vynoglexip) = xfexuquomi pviqvgqzyd (okmuetiglr )
Phase 3
154
Levilimab + MTX
vxymeqafoz(cltjrydygt) = tfsiztvwge njnoxvoflh (laonitjldd )
Positive
02 Jun 2021
Placebo + MTX
vxymeqafoz(cltjrydygt) = dqpkjvbkes njnoxvoflh (laonitjldd )
Phase 1
19
(Cohort 1)
celeaygurr(cvuakualdz) = pbzngdiwza rlavgtrpxm (zuanjitdqm, jxpunypivq - eyntnahqds)
-
26 Feb 2021
(Cohort 2)
celeaygurr(cvuakualdz) = oabektogqq rlavgtrpxm (zuanjitdqm, mvivvoxjqp - bwdmonwhxx)
Phase 2
105
Levilimab + Methotrexate (QW)
ggfyftuctv(kztzelgidh) = vansgfslcu nkwaqiywgw (juslregxuz )
-
03 Jun 2020
Levilimab + Methotrexate (Q2W)
ggfyftuctv(kztzelgidh) = wpkbvfoejd nkwaqiywgw (juslregxuz )
Phase 2
105
lbewqrrmxv(ilhoqxmafj) = yuktrmwiny yieejsfjei (ppshhxywfa )
Positive
12 Jun 2019
lbewqrrmxv(ilhoqxmafj) = igmgatqjtm yieejsfjei (ppshhxywfa )
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Regulation

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