Last update 01 Nov 2024

Taurolidine/Heparin sodium

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
DefenCath, Neutrolin
Mechanism
AT III activators(Antithrombin-III activators), LPS inhibitors(Lipopolysaccharide (LPS) inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (15 Nov 2023),
RegulationFast Track (US), Qualified Infectious Disease Product (US), Priority Review (US)
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Structure

Molecular FormulaC7H16N4O4S2
InChIKeyAJKIRUJIDFJUKJ-UHFFFAOYSA-N
CAS Registry19388-87-5
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Catheter-Related Infections
US
15 Nov 2023
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hematologic DiseasesPreclinical
US
27 Jun 2024
NeoplasmsPreclinical
US
27 Jun 2024
Kidney Failure, ChronicDiscovery
US
01 Dec 2015
SepsisDiscovery
US
01 Dec 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
797
(bcqdqprzxq) = mqsbwfdlbm qnrnndmxhf (wwtzzsydlt, 0.07 - 0.26)
Superior
15 Nov 2023
(bcqdqprzxq) = npmahsubyx qnrnndmxhf (wwtzzsydlt, 0.33 - 0.66)
Phase 3
806
(Neutrolin Arm)
mibnouzskk(jjsecuxczv) = ypwjjqcusp mtastcrvij (uzisxiytem, mpkbzmbpww - ucqmyljxys)
-
31 Aug 2021
(Heparin Arm)
mibnouzskk(jjsecuxczv) = kwqkwwhflm mtastcrvij (uzisxiytem, tuxtqtnnbf - oaaqqbzqvc)
Not Applicable
-
60
gpmvqmzlbi(aclgmsmsai) = yccfbdvymo kaeeegnyya (lrwgsupdsp )
Positive
21 May 2015
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Approval

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Regulation

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