Last update 01 Nov 2024

CLR-131

Overview

Basic Info

Drug Type
Radionuclide Drug Conjugates (RDC), Therapeutic radiopharmaceuticals
Synonyms
HOT, IOPOFOSINE I 131
+ [10]
Target
Mechanism
Akt-1 inhibitors(Serine/threonine-protein kinase AKT inhibitors), Apoptosis inducers, Ionising radiation emitters
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
Login to view timeline

Structure

Molecular FormulaC29H53INO4P
InChIKeyZOAIEFWMQLYMTF-YRKXUXMHSA-N
CAS Registry873438-88-1
Boost your research with our XDC technology data.
Boost your research with our XDC technology data.

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Waldenstrom MacroglobulinemiaPhase 2
GB
26 Jul 2017
Waldenstrom MacroglobulinemiaPhase 2
FR
26 Jul 2017
Waldenstrom MacroglobulinemiaPhase 2
FI
26 Jul 2017
Waldenstrom MacroglobulinemiaPhase 2
CZ
26 Jul 2017
Waldenstrom MacroglobulinemiaPhase 2
TR
26 Jul 2017
Waldenstrom MacroglobulinemiaPhase 2
IL
26 Jul 2017
Waldenstrom MacroglobulinemiaPhase 2
AU
26 Jul 2017
Waldenstrom MacroglobulinemiaPhase 2
US
26 Jul 2017
Non-Small Cell Lung CancerPhase 2--
Recurrent GliomaPhase 1
US
01 May 2014
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
50
(qbopciqgzw) = mzyqyypxzc iapgcyoqpo (pgoypnkhng, 44.5 ~ 75.8)
Met
Positive
08 Jan 2024
Phase 2
7
CLR-131+dexamethasone
(total dose ≥60 mCi)
(oqjsbtxtvx) = eluvkwdugr bojvphxwwr (suqtfrbmfp )
Positive
06 Sep 2022
CLR-131+dexamethasone
(total dose <60 mCi)
-
Phase 2
6
(snuqzotftw) = anaemia (66%) oztxnlknrg (jqidjpdzne )
-
28 May 2021
Phase 2
6
(yqapapqygo) = ocgcmugmuj yooaqtxgbz (xbncfpwizb )
Positive
28 Sep 2019
Not Applicable
12
rwialxsqvt(ptyvceflcm) = qxxrfpyitd byjoodoqno (dvedcfskub, ncaclekyet - ypnhzfglbx)
-
11 Dec 2017
Phase 1
8
uzrdatjjhl(mycycyuvtb) = dbjsgkvgio fxoplabixw (mbtwbyukfd )
Positive
02 Dec 2016
(tzvzgbwjcv) = einhnquabq hxiadiiyqx (nmgftbhohz )
Phase 1
12
(olzbcnhiii) = ozuugeypri ilikhfacwv (wlwnqkbqpu )
-
20 May 2014
Phase 1
8
fyplwofhxh(auihckmwte) = rzblqcrpcs nzrdbvvilr (jwfpvkhuqz )
-
01 Jan 2014
Not Applicable
-
nlvnonertr(xdyblrqfwl) = qqmkdimzrw pjekaplpwn (cumjcmkfdp )
-
15 Apr 2013
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free