Last update 01 Nov 2024

Povetacicept

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
povetacicept
Mechanism
APRIL inhibitors(Tumor necrosis factor ligand superfamily member 13 inhibitors), BAFF inhibitors(B-cell-activating factor/B lymphocyte stimulator inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glomerulonephritis, IGAPhase 3
US
30 Aug 2024
Glomerular diseasePhase 2
PR
15 Mar 2023
Glomerulonephritis, MembranousPhase 2
KR
15 Mar 2023
Glomerulonephritis, MembranousPhase 2
US
15 Mar 2023
Glomerulonephritis, MembranousPhase 2
AU
15 Mar 2023
Glomerulonephritis, MembranousPhase 2
PR
15 Mar 2023
Lupus NephritisPhase 2
US
15 Mar 2023
Lupus NephritisPhase 2
AU
15 Mar 2023
Lupus NephritisPhase 2
PR
15 Mar 2023
Lupus NephritisPhase 2
KR
15 Mar 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Glomerulonephritis, IGA
galactose-deficient IgA1 (Gd-IgA1)
12
(lajwttjobn) = Povetacicept has been well tolerated, with the majority of treatment-emergent adverse events being of low grade and none leading to treatment discontinuation or dose reduction/interruption. gxagjqpqnp (nddrkmugmh )
Positive
01 Apr 2024
Phase 1/2
13
(hqfmwjpxug) = jlovvdmryu rbytonqiar (sqdqxwkkah )
Positive
02 Nov 2023
Phase 1/2
-
(mpkpjwmhbz) = in the first IgAN dose cohort (80 mg subcutaneously once every 4 weeks) has been safe and well-tolerated to date, with no serious or severe adverse events, no events of hypogammaglobulinemia (IgG < 3g/L), and no instances of hypersensitivity or administration-related reactions. dngacvjnkr (dcyvcjkyad )
Positive
30 Aug 2023
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Regulation

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